Year 1 | Year 2 | Year 3 | |
---|---|---|---|
(August 2009 to July 2010) | (August 2010 to July 2011) | (August 2011 to July 2012) | |
Number of prescriptions reviewed | 1,414 | 1,168 | 1,567 |
Number of antimicrobial stewardship recommendations made (percentage of prescriptions reviewed) | 649 (45.9%) | 363 (31.1%)b | 557 (35.5%) |
• Discontinuation of antibiotic therapy | 239 | 135 | 227 |
• De-escalation of antibiotic therapy | 198 | 74 | 176 |
• Intravenous to enteral switch | 49 | 10 | 47 |
• Escalation of antibiotic therapy | 25 | 7 | 13 |
• Antibiotic dosing | 39 | 68 | 49 |
• Othersa | 99 | 69 | 45 |
Recommendation acceptance (percentage of recommendations accepted) | 570 (87.7%) | 266 (73.3%)b | 464 (83.3%) |
Antimicrobial prescription (defined daily dose/1,000 inpatient-days) | |||
• All intravenous antibiotics | 468.6 | 580.3c | 513.7 |
• All carbapenems | 130.8 | 181.2c | 149.1 |
• 3rd and 4th-generation cephalosporins | 128.2 | 95.1d | 108.7 |
• Piperacillin/tazobactam | 62.2 | 116.0c | 160.8 |
• Vancomycin | 80.9 | 108.7e | 38.1 |