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Table 1 Descriptive characteristics of cases with ICU-acquired LRTI and control patients without LRTI

From: Attributable costs of ventilator-associated lower respiratory tract infection (LRTI) acquired on intensive care units: a retrospectively matched cohort study

Characteristic Cases (N = 49) Controls (N = 49) P-value*
SAPS II† 48 (36–64) 50 (38–61) 0.535
Age† 63 (53–75) 63 (54–75) 0.455
Males † 30 (62%) 30 (62%) 1.000
Time with mechanical ventilation (h) 444 (182–682) 84 (0–304) <.001
  Surgical ICU 37 (76%) 23 (47%) 0.005
  Medical ICU 6 (12%) 16 (33%)
  Interdisciplinary ICU 6 (12%) 10 (20%)
In-house mortality 14 (29%) 2 (4%) 0.002
Charlson comorbidity index 7 (4–8) 5 (3–8) 0.350
Myokardial infarct 3 (6%) 0 (0%) 0.250
Congestive heart failure 24 (49%) 19 (39%) 0.359
Peripheral vascular disease 11 (22%) 5 (10%) 0.109
Cerebrovascular disease 23 (47%) 16 (33%) 0.265
Dementia 2 (4%) 1 (2%) 1.000
Chronic lung disease 11 (22%) 9 (18%) 0.791
Connective tissue disease 1 (2%) 0 1.000
Peptic ulcer 0 1 (2%) 1.000
Mild liver disease 6 (12%) 6 (12%) 1.000
Diabetes without complications 12 (25%) 8 (16%) 0.388
Diabetes with complications 2 (4%) 2 (4%) 1.000
Renal disease 25 (51%) 14 (29%) 0.027
Tumour 5 (10%) 13 (27%) 0.057
Moderate or severe liver disease 4 (8%) 5 (10%) 1.000
Malignant tumour 2 (4%) 6 (12%) 0.219
AIDS 0 1 (2%) 1.000
Hemiplegia 16 (33%) 8 (16%) 0.096
Leukemia 1 (2%) 0 1.000
Lymphoma 0 0 1.000
  1. SAPS II, simplified acute physiology score; AIDS, acquired immunodeficiency syndrome; LOS, length of hospital stay in days.
  2. Values are given as number (%) or median (interquartile range).
  3. * Wilcoxon signed-rank test for continuous variables and McNemar’s test for binary variables.
  4. † Matching criteria. Additional matching criteria were: discharge within 2010 and a length of stay at least as that of cases before onset of LRTI.
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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