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Table 2 Mechanisms of resistance found in C. difficile type 078 isolates

From: Antimicrobial susceptibility profiles of human and piglet Clostridium difficile PCR-ribotype 078

 Antibiotic Origin of isolatea(total number)  Mechanism of resistance N. of positive isolates (%)
Tetracycline Human (6) tet(M) 6 (100%)
Porcine (8) 8 (100%)
Erythromycin Human (29) erm(B) 3 (10%)
Porcine (38) 0 (0%)
Clindamycin Human (3) erm(B) 3 (100%)
Porcine (1) 0 (0%)
Moxifloxacin Human (8) Aminoacid substitution in GyrA 8 (100%)
Porcine (7) 4 (57%)
  1. a: All isolates with tetracycline MIC ≥8 mg/L (n=14), erythromycin MIC ≥4 mg/L (n=67) or clindamycin MIC ≥4 mg/L (n=4) were analysed for resistance mechanisms. Seven of eight porcine isolates with moxifloxacin MIC ≥4 mg/L were tested for mutations.