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Table 2 Activity of three hand disinfectants against adenovirus type 5 and poliovirus type 1 according to EN 14476 with various types of organic load and various product concentrations in the test

From: Efficacy of hand rubs with a low alcohol concentration listed as effective by a national hospital hygiene society in Europe

Product

Active ingredient(s) (concentration; all w/w)

Test virus

Product concentration in test

Organic load

Mean log10-reduction of viral infectivity

30 s

60 s

120 s

180 s

Product 1

Ethanol (70%)

adenovirus

80%

PBS

0.13

0.63

2.75

n.a.

80%

PBS

0.88

1.75

3.25

≥ 4.25

80%

PBS

1.13

2.75

≥ 4.25

≥ 5.00

80%

clean conditions

1.63

3.25

≥ 4.63

n.a.

90%

none

1.25

2.13

≥ 4.00

n.a.

poliovirus

80%

PBS

0

0.13

n.a.

0.13

80%

PBS

0.13

0.25

0

0

80%

PBS

0.37

0.37

0.87

0.87

80%

clean conditions

0

0.12

n.a.

0

90%

none

0

0

n.a.

0.87

Product 2

Ethanol (70%)

adenovirus

80%

PBS

≥ 5.13

≥ 5.13

≥ 5.13

n.a.

80%

clean conditions

≥ 5.38

≥ 5.38

≥ 5.38

n.a.

90%

none

≥ 5.63

≥ 5.63

≥ 5.63

n.a.

poliovirus

80%

PBS

0.13

0

n.a.

1.25

80%

clean conditions

0

0.12

n.a.

0.75

90%

none

0

1.75

n.a.

3.25

Product 3

Ethanol (60%), Isopropanol (15%)

adenovirus

80%

PBS

0

0.37

0.62

n.a.

97%

clean conditions

0.62

1.50

≥ 3.50

n.a.

poliovirus

80%

PBS

n.a.

0.38

0.50

0.38

97%

clean conditions

n.a.

0

1.75

2.63

  1. n.a., Data not available.