Product | Active ingredient(s) (concentration; all w/w) | Test virus | Product concentration in test | Organic load | Mean log10-reduction of viral infectivity | |||
---|---|---|---|---|---|---|---|---|
30 s | 60 s | 120 s | 180 s | |||||
Product 1 | Ethanol (70%) | adenovirus | 80% | PBS | 0.13 | 0.63 | 2.75 | n.a. |
80% | PBS | 0.88 | 1.75 | 3.25 | ≥ 4.25 | |||
80% | PBS | 1.13 | 2.75 | ≥ 4.25 | ≥ 5.00 | |||
80% | clean conditions | 1.63 | 3.25 | ≥ 4.63 | n.a. | |||
90% | none | 1.25 | 2.13 | ≥ 4.00 | n.a. | |||
poliovirus | 80% | PBS | 0 | 0.13 | n.a. | 0.13 | ||
80% | PBS | 0.13 | 0.25 | 0 | 0 | |||
80% | PBS | 0.37 | 0.37 | 0.87 | 0.87 | |||
80% | clean conditions | 0 | 0.12 | n.a. | 0 | |||
90% | none | 0 | 0 | n.a. | 0.87 | |||
Product 2 | Ethanol (70%) | adenovirus | 80% | PBS | ≥ 5.13 | ≥ 5.13 | ≥ 5.13 | n.a. |
80% | clean conditions | ≥ 5.38 | ≥ 5.38 | ≥ 5.38 | n.a. | |||
90% | none | ≥ 5.63 | ≥ 5.63 | ≥ 5.63 | n.a. | |||
poliovirus | 80% | PBS | 0.13 | 0 | n.a. | 1.25 | ||
80% | clean conditions | 0 | 0.12 | n.a. | 0.75 | |||
90% | none | 0 | 1.75 | n.a. | 3.25 | |||
Product 3 | Ethanol (60%), Isopropanol (15%) | adenovirus | 80% | PBS | 0 | 0.37 | 0.62 | n.a. |
97% | clean conditions | 0.62 | 1.50 | ≥ 3.50 | n.a. | |||
poliovirus | 80% | PBS | n.a. | 0.38 | 0.50 | 0.38 | ||
97% | clean conditions | n.a. | 0 | 1.75 | 2.63 |