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Table 1 Factors associated with ESBL-E carriage amongst 1072 internal medicine patients, University of Geneva Hospitals, March-June 20101; univariate and multivariate regression analysis

From: Carriage of extended-spectrum beta-lactamase-producing enterobacteriacae among internal medicine patients in Switzerland

 

Proportions (n)

Univariate regression

Multivariate regression

Variable

ESBL carriage (n = 51)

No ESBL carriage (n = 1021)

OR [95% CI]

P- value

OR [95% CI]

P- value

Male gender

54.9 (28)

56.9 (581)

0.92 [0.52-1.62]

0.778

  

Transferred from ICU

0

0.6 (6)

0.27 [0.36-1.97]

0.195

  

Transferred from other ward (other than the ICU)

2.0 (1)

2.5 (25)

0.80 [0.11-6.00]

0.825

  

Patient admitted from home

96.1 (49)

90.7 (925)

2.52 [0.61-10.62]

0.201

  

Age

 < =59 y

37.3 (19)

33.6 (343)

1.94 [0.55-6.81]

0.300

  

 60 -79 y

41.2 (21)

39.5 (403)

1.62 [0.47-5.52]

0.443

  

 > = 80 y

21.5 (11)

22.1 (226)

1.40 [0.38-5.2]

0.614

  

Acute renal failure2

20.8 (5)

23.0 (94)

0.87 [0.32-2.40]

0.793

  

Chronic renal failure2

16.7 (4)

13.6 (55)

1.28 [0.42-3.87]

0.667

  

End stage renal failure2

4.2 (9)

2.0 (8)

2.16 [0.26-18.04]

0.476

  

Diabetes without complications 2

33.3 (8)

15.3 (62)

2.77 [1.14-6.39]

0.033

2.87 [1.09-7.08]

0.032

Diabetes mellitus (with complications)2

12.5 (3)

10.3 (42)

1.24 [0.35- 4.33]

0.706

  

Peripheral vascular disease2

8.3 (16)

3.9 (16)

2.21 [0.48-10.25]

0.309

  

Chronic obstructive airway disease2

20.8 (5)

13.8 (56)

1.64 [0.59-4.58]

0.341

  

Dementia2

0

1.2 (5)

Omitted

   

Stroke2

0

1.0 (4)

Omitted

   

Cerebral hemorrhage2

0

0.5 (2)

Omitted

   

Congestive cardiac failure2

29.2 (7)

23.7 (96)

1.33 [0.54-3.30]

0.539

  

Ischemic heart disease2

12.5 (3)

11.1 (45)

1.15 [0.33-4.00]

0.831

  

Hematological malignancy2

0

5.4 (22)

Omitted

   

Carotid artery stenosis2

0

1.0 (4)

Omitted

   

Parkinson’s disease2

0

0.3 (1)

Omitted

   

Connective tissue disease 2

8.3 (5)

1.0 (4)

9.14 [1.58-52.62]

0.013

7.22 [1.17-44.59]

0.033

Liver failure 2

8.3 (6)

1.5 (6)

6.06 [1.15-31.77]

0.033

8.39 [1.55-45.45]

0.014

Respiratory failure2

0

0.7 (3)

Omitted

   

Solid organ cancer2

4.2 (1)

17.0 (69)

0.21 [0.28-1.58]

0.130

  

Metastatic cancer2

8.3 (2)

8.4 (34)

0.99 [0.22-4.41]

0.994

  

Peptic ulcer disease2

4.2 (1)

2.7 (11)

1.56 [0.19-12.64]

0.676

  

Infection2

0

0.9 (4)

Omitted

   
  1. 1. Positive ESBL swab at admission in cases where the swab was collected within 48 h of admission and patients with prior carriage have been excluded.
  2. ICU intensive care unit, y years;
  3. 2. Denominator adjusted for number of patients in whom data were available.