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Table 1 Antimicrobial resistance rates and MIC values for Clostridium difficile isolates from different countries

From: Epidemiology of Clostridium difficile infection in Asia

(Reference) Number of isolates [Resistance rate] (%), MIC50 (mg/L), MIC90 (mg/L)
Erythromycin Clindamycin Tetracycline Moxifloxacin Ciprofloxacin Piperacillin/ tazobactam Metronidazole Vancomycin
China          
[37] 75 [76], 128, 128 [66.7], 128, 128 [41.3], 4, 64 [45.3], 4, 128 [100], 64, 128 [0], <16/4, 16/4 [0], 0.25, 0.25 [0], 1, 2
[39] 110 [85.3], 128, 128 [88.1], 128, 128 [62.7], 16, 32 [61.8], 16, 128 [100], 64, 128 [0], 8/4, 16/4 [0]a, 0.125, 0.25 [0], 0.5, 1
Hong Kong          
[40] 35      [100]   0.5, 0.75 0.75, 1.5
Japan          
[77] 73 [87.7], >256, >256 [87.7], >256, >256    [100], >32, >32   [0], 0.19, 0.25 [0], 2, 4
[16] 72     [12]b [100]   [0] [0]
Korea          
[31] 120   [50], 128, >128   [42], 2, 16   [0], 8, 16 [0], 1,4 [0], 0.5, 1
[19] 111   [82]   [83]     
[33] 131   [67.9]   [82]    [0] [0]
[78] 123   [75]   [85]     
Singapore          
[60] 68   [63], 8, >512      [0], 0.5, 1 [0], 1, 1
Taiwan          
[79] 60   [73.3], 16, 64 [41.7], 8, >16 [30] [100]    
[47] 113   [46], 4, >256   [16]    [0]  
  1. a 18 isolates showed heteroresistance to metronidazole, bsubset of 25 isolates tested
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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