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Table 1 Antimicrobial resistance rates and MIC values for Clostridium difficile isolates from different countries

From: Epidemiology of Clostridium difficile infection in Asia

(Reference)

Number of isolates

[Resistance rate] (%), MIC50 (mg/L), MIC90 (mg/L)

Erythromycin

Clindamycin

Tetracycline

Moxifloxacin

Ciprofloxacin

Piperacillin/ tazobactam

Metronidazole

Vancomycin

China

         

[37]

75

[76], 128, 128

[66.7], 128, 128

[41.3], 4, 64

[45.3], 4, 128

[100], 64, 128

[0], <16/4, 16/4

[0], 0.25, 0.25

[0], 1, 2

[39]

110

[85.3], 128, 128

[88.1], 128, 128

[62.7], 16, 32

[61.8], 16, 128

[100], 64, 128

[0], 8/4, 16/4

[0]a, 0.125, 0.25

[0], 0.5, 1

Hong Kong

         

[40]

35

    

[100]

 

0.5, 0.75

0.75, 1.5

Japan

         

[77]

73

[87.7], >256, >256

[87.7], >256, >256

  

[100], >32, >32

 

[0], 0.19, 0.25

[0], 2, 4

[16]

72

   

[12]b

[100]

 

[0]

[0]

Korea

         

[31]

120

 

[50], 128, >128

 

[42], 2, 16

 

[0], 8, 16

[0], 1,4

[0], 0.5, 1

[19]

111

 

[82]

 

[83]

    

[33]

131

 

[67.9]

 

[82]

  

[0]

[0]

[78]

123

 

[75]

 

[85]

    

Singapore

         

[60]

68

 

[63], 8, >512

    

[0], 0.5, 1

[0], 1, 1

Taiwan

         

[79]

60

 

[73.3], 16, 64

[41.7], 8, >16

[30]

[100]

   

[47]

113

 

[46], 4, >256

 

[16]

  

[0]

 
  1. a 18 isolates showed heteroresistance to metronidazole, bsubset of 25 isolates tested