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Table 2 Comparison of the microbiological characteristics of cases ( E. faecium ) and controls

From: Algorithm for pre-emptive glycopeptide treatment in patients with haematologic malignancies and an Enterococcus faecium bloodstream infection

 

Cases (n = 33)

Controls (n = 66)

p-value

Colonization with E. faeciuma

   

   7 days prior to blood culture

13 (39.4%)

10 (15.2%)

0.007

   30 days prior to blood culture

19 (57.6%)

14 (21.2%)

<0.001

   90 days prior to blood culture

21 (63.6%)

16 (24.2%)

<0.001

   Number of faeces cultures with E. faecium 30 days prior to blood culture, median (range)

1 (0–8)

0 (0–6)

<0.001

Type of blood culture

   

    Polymicrobial b

3 (9.1%)

1 (1.5%)

0.107

    Galactomannan

3 (9.1%)

2 (3.0%)

0.330

Clinical source of infection

   

   Abdominal focus: abdominal pain and/or diarrhea

25 (75.8%)

29 (43.9%)

0.003

    Abdominal pain

9 (27.3%)

11 (16.7%)

0.215

    Diarrhea

23 (69.7%)

26 (39.4%)

0.004

   Mucositis

13 (39.4%)

18 (27.3%)

0.220

   Lungs

   

   Coughing and/or sputum

8 (24.2%)

15 (22.7%)

0.866

   Radiological proof of pneumonia or lung infiltrates

4 (12.1%)

14 (21.2%)

0.269

   Ear Nose Throat

1 (3.0%)

2 (3.0%)

1.000

   Skin

7 (21.2%)

19 (28.8%)

0.419

   Urinary infection

1 (3.0%)

9 (13.6%)

0.158

  1. aIn faeces culture, part of the SDD regimen. bWithin ± 7 days, less pathogenic micro-organisms (coagulase-negative staphylococci, corynebacteria, micrococcus spp. and bacillus spp.) are excluded.