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Table 2 Comparison of the microbiological characteristics of cases ( E. faecium ) and controls

From: Algorithm for pre-emptive glycopeptide treatment in patients with haematologic malignancies and an Enterococcus faecium bloodstream infection

  Cases (n = 33) Controls (n = 66) p-value
Colonization with E. faeciuma    
   7 days prior to blood culture 13 (39.4%) 10 (15.2%) 0.007
   30 days prior to blood culture 19 (57.6%) 14 (21.2%) <0.001
   90 days prior to blood culture 21 (63.6%) 16 (24.2%) <0.001
   Number of faeces cultures with E. faecium 30 days prior to blood culture, median (range) 1 (0–8) 0 (0–6) <0.001
Type of blood culture    
    Polymicrobial b 3 (9.1%) 1 (1.5%) 0.107
    Galactomannan 3 (9.1%) 2 (3.0%) 0.330
Clinical source of infection    
   Abdominal focus: abdominal pain and/or diarrhea 25 (75.8%) 29 (43.9%) 0.003
    Abdominal pain 9 (27.3%) 11 (16.7%) 0.215
    Diarrhea 23 (69.7%) 26 (39.4%) 0.004
   Mucositis 13 (39.4%) 18 (27.3%) 0.220
   Lungs    
   Coughing and/or sputum 8 (24.2%) 15 (22.7%) 0.866
   Radiological proof of pneumonia or lung infiltrates 4 (12.1%) 14 (21.2%) 0.269
   Ear Nose Throat 1 (3.0%) 2 (3.0%) 1.000
   Skin 7 (21.2%) 19 (28.8%) 0.419
   Urinary infection 1 (3.0%) 9 (13.6%) 0.158
  1. aIn faeces culture, part of the SDD regimen. bWithin ± 7 days, less pathogenic micro-organisms (coagulase-negative staphylococci, corynebacteria, micrococcus spp. and bacillus spp.) are excluded.