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Table 2 Proportion of variance (R 2 ) in state level antimicrobial prescribing that could be explained by MRSA wound infection rates at the state and national levels

From: Optimizing antimicrobial prescribing: Are clinicians following national trends in methicillin-resistant staphylococcus aureus (MRSA) infections rather than local data when treating MRSA wound infections

State level

State level

National level

State level infection

National level infection

antimicrobial

infection rate (R2)a

infection

rate (Coefficient of

rate (Coefficient of

prescribing rate

 

rate (R2)a

partial determination)b

partial determination)b

Trimethoprim-sulfamethoxazole

<0.001

0.03

0.10

0.004

Cephalexin

<0.001

0.01

0.08

0.003

Linezolid

0.004

0.22

0.004

0.22

Clindamycin

<0.001

0.17

0.10

0.008

  1. aR2 represents the unadjusted proportion of variance in prescribing that could be explained by MRSA rates using population weighted linear regression; bCoefficient of Partial Determination represents the marginal effect of MRSA infection on prescribing when time was already accounted for in the model.
  2. Source: Author’s calculations with susceptibility information from The Surveillance Network® (TSN) and prescription data derived from IMS Health Xponent™ January 1999-December 2007, IMS Health Incorporated. All Rights Reserved.