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Table 1 Comparison of ESBL-EC and ESBL-KP with respect to molecular characteristics and susceptibility profiles

From: Differences in risk-factor profiles between patients with ESBL-producing Escherichia coli and Klebsiella pneumoniae: a multicentre case-case comparison study

  ESBL-EC (%) ESBL-KP (%) P value
aac(6’)-Ib-cr 41/95 (43.1) 61/81 (75.3) <0.0001
qnrB 11/95 (11.6) 65/81 (80.2) <0.0001
bla CTX-M-15 58/95 (61.1) 70/81 (86.4) 0.0002
bla CTX-M-14 28/95 (29.5) 2/81 (2.5) <0.0001
bla TEM-1 53/95 (55.8) 20/81 (24.7) <0.0001
bla OXA 42/95 (44.2) 50/81 (61.7) 0.024
Other blaCTX-M 4/95 (4.2) 1/81 (1.2) 0.38
Non blaCTX-M ESBLs 5/95 (5.3) 8/81 (9.9) 0.26
Gentamicin NS 53/95 (55.8) 66/81 (81.5) 0.0003
Trimethoprim-sulfamethoxazole NS 67/95 (70.5) 78/81 (96.3) <0.0001
Fluoroquinolone NS 66/95 (69.5) 62/81 (76.5) 0.31
NS ≥ 4 antibiotic classes 36/95 (37.9) 55/81 (67.9) <0.0001
  1. NS, non-susceptible. Representative antibiotics for the three non-beta-lactam antibiotic classes tested were: gentamicin; trimethoprim-sulfamethoxazole, ciprofloxacin. All isolates were assumed by definition to be resistant to cephalosporins.