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Table 1 Comparison of ESBL-EC and ESBL-KP with respect to molecular characteristics and susceptibility profiles

From: Differences in risk-factor profiles between patients with ESBL-producing Escherichia coli and Klebsiella pneumoniae: a multicentre case-case comparison study

 

ESBL-EC (%)

ESBL-KP (%)

P value

aac(6’)-Ib-cr

41/95 (43.1)

61/81 (75.3)

<0.0001

qnrB

11/95 (11.6)

65/81 (80.2)

<0.0001

bla CTX-M-15

58/95 (61.1)

70/81 (86.4)

0.0002

bla CTX-M-14

28/95 (29.5)

2/81 (2.5)

<0.0001

bla TEM-1

53/95 (55.8)

20/81 (24.7)

<0.0001

bla OXA

42/95 (44.2)

50/81 (61.7)

0.024

Other blaCTX-M

4/95 (4.2)

1/81 (1.2)

0.38

Non blaCTX-M ESBLs

5/95 (5.3)

8/81 (9.9)

0.26

Gentamicin NS

53/95 (55.8)

66/81 (81.5)

0.0003

Trimethoprim-sulfamethoxazole NS

67/95 (70.5)

78/81 (96.3)

<0.0001

Fluoroquinolone NS

66/95 (69.5)

62/81 (76.5)

0.31

NS ≥ 4 antibiotic classes

36/95 (37.9)

55/81 (67.9)

<0.0001

  1. NS, non-susceptible. Representative antibiotics for the three non-beta-lactam antibiotic classes tested were: gentamicin; trimethoprim-sulfamethoxazole, ciprofloxacin. All isolates were assumed by definition to be resistant to cephalosporins.