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Table 1 Selected studies that specifically assessed the role of hand hygiene enhancement on methicillin-resistant Staphylococcus aureus rates

From: The effect of improved hand hygiene on nosocomial MRSA control

First author and year

Trial design

Setting

Hand hygiene enhancement strategy

Other interventions to reduce MRSA

Pittet et al. [3]

Quasi-experimental

Hospital-wide

ABHR, staff education, reminders, performance feedback and administrative involvement

On-site surveillance, implementation of prevention guidelines, outbreak investigations, and environmental sanitization

Johnson et al. [5]

Quasi-experimental

Hospital-wide

ABHR, staff education, reminders, performance and feedback and culture change program

Enhanced cleaning of healthcare equipment, and decolonization of MRSA patients

Grayson et al. [7]

Quasi-experimental

Multiple hospitals

ABHR, education, performance feedback and recommendations for culture change

Individual hospitals observed various MRSA control measures

Stone et al. [10]

Prospective ecological

Acute NHS hospital trusts, United Kingdom

ABHR, reminders, audit and performance feedback and patient empowerment

Saving lives campaign, Health Act 2006, and visit to trusts by Department of Health improvement team

Kirkland et al. [11]

Before and after study

Hospital-wide

Leadership accountability, measurement/performance feedback, ABHR, education/training and marketing/communication

None reported

Lee et al. [15]

Prospective interventional cohort study

Surgical wards

Hand hygiene improvement program as per WHO guideline

Screening and contact isolation and targeted decolonization

Derde et al. [17]

Hybrid prospective interventional cohort study and RCT

Intensive care units

Hand hygiene improvement program as per WHO guideline

Universal decolonization in phase 2 and screening and isolation in phase 3

  1. Abbreviations: MRSA methicillin-resistant Staphylococcus aureus, ABHR alcohol-based handrubs, NHS National Health Service, RCT randomized controlled trial.