Table 1 Factors associated with catheter-associated urinary tract infections caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli versus non-ESBL-producing E. coli

Mean (range) age, in years

70.4 (24-98)

67.5 (18-103)

67.9 (18-103)

*0.003^b

1.01 (1.00, 1.02)

Gender (reference, female)

0.01

1.22 (0.91, 1.65)

Male (n (%))

86 (31.7%)

462 (24.4%)

548 (25.3%)

Female (n (%))

185 (68.3%)

1431 (75.6%)

1616 (74.7%)

HIV Positive

5 (1.9%)

12 (0.6%)

17 (0.8%)

0.052^c

2.09 (0.66, 6.55)

Diabetes

89 (32.8%)

522 (27.6%)

611 (28.2%)

0.07

NA

Urinary Tract Disease

226 (83.4%)

1420 (75.0%)

1646 (76.1%)

0.003

1.43 (1.01, 2.03)

Malignancy

59 (21.8%)

363 (19.2%)

422 (19.5%)

0.31

NA

Mean (range) Duration of Catheterization Prior to CAUTI Onset, in days (Mean)

7.74 (0-78)

6.32 (0-124)

6.50 (0-124)

*0.03^b

0.99 (0.98, 1.01)

Urinary Tract Procedure

26 (9.59%)

113 (5.97%)

139 (6.42%)

0.02

1.43 (0.88, 2.32)

Mean (range) Charlson Comorbidity Score

7.73 (0-35)

6.76 (0-51)

6.88 (0-51)

0.001^d

1.03 (0.99, 1.06)

Antibiotics Received Prior to CAUTI Onset

174 (64.2%)

804 (42.5%)

978 (45.2%)

<0.0001

NA

Aminoglycoside

27 (9.9%)

73 (3.9%)

100 (4.6%)

<0.0001

5.42 (1.77, 16.55)

Cephalosporin, 1^st Gen.

66 (24.4%)

346 (18.3%)

412 (19.0%)

0.02

2.34 (1.63, 3.36)

Cephalosporin, 3^rd Gen.

23 (8.5%)

29 (1.5%)

52 (2.4%)

<0.0001

2.89 (0.79, 10.67)

Macrolide

22 (8.1%)

69 (3.7%)

91 (4.2%)

0.001

2.39 (1.12, 5.08)

Penicillin, 2^nd Gen.

17 (6.3%)

91 (4.8%)

108 (5.0%)

0.30

NA

Penicillin, 4^th Gen.

50 (18.5%)

173 (9.1%)

223 (10.3%)

<0.0001

2.65 (1.48, 4.76)

Vancomycin

59 (21.8%)

203 (10.7%)

262 (12.1%)

<0.0001

3.40 (2.26, 5.12)