Table 4 Explanatory factors related to antibiotic use (number of discharges as denominator) in 22 Norwegian Health Enterprises, 2006–2011, derived from six multiple linear regression models
Independent variables | WHO DDDs/100 discharges | Hospital-adjusted DDDs/100 discharges | ||||
|---|---|---|---|---|---|---|
All antibiotics | Broad-spectruma | All penicillinsb | All antibiotics | Broad-spectruma | All penicillinsb | |
Overall model, R 2 (adjusted R 2 ) | 0.71 (0.67) | 0.30 (0.22) | 0.68 (0.65) | 0.71 (0.68) | 0.34 (0.26) | 0.72 (0.69) |
Infect. disease ICD-10 main diag. (%) | ||||||
Regression coeff. (95% confidence interval (C.I.)) | 30.6*** (15.9; 45.2) | 21.9*** (10.0; 33.8) | 16.4*** (7.5; 25.4) | 8.95*** (4.3; 13.6) | ||
Beta weight | 0.44 | 0.45 | 0.36 | 0.44 | ||
Increment in R2 | 0.0588 | 0.0614 | 0.0406 | 0.0591 | ||
Registered nurses per 100 beds | ||||||
Regression coeff. (95% C.I.) | 0.78*** (0.37; 1.20) | 0.46*** (0.21; 0.72) | 0.49*** (0.21; 0.77) | 0.17** (0.07; 0.27) | ||
Beta weight | 0.43 | 0.36 | 0.42 | 0.43 | ||
Increment in R2 | 0.0657 | 0.0463 | 0.0625 | 0.0357 | ||
Hospital stay > 10 days (%) | ||||||
Regression coeff. (95% (C.I.) | 12.1** (5.1; 19.2) | 2.38** (0.9; 3.86) | 7.46* (1.2; 13.7) | 8.27*** (4.4; 12.2) | 2.75** (1.2; 4.3) | 2.99*** (0.4; 5.6) |
Beta weight | 0.48 | 0.45 | 0.42 | 0.51 | 0.56 | 0.41 |
Increment in R2 | 0.0861 | 0.0753 | 0.0663 | 0.0956 | 0.1157 | 0.0616 |
University hospital (binary) | ||||||
Regression coeff. (95% C.I.) | −47.6*** (−84.6; −10.7) | −9.8** (−15.5; −4.1) | −33.6*** (−51.1; −16.2) | −10.9*** (−14.5; −7.2) | ||
Beta weight | −0.36 | −0.35 | −0.39 | −0.42 | ||
Increment in R2 | 0.0458 | 0.0441 | 0.0545 | 0.0626 | ||
Surgical DRGs c per 100 beds | ||||||
Regression coeff. (95% C.I.) | 2.43* (0.2; 4.6) | |||||
Beta weight | 0.35 | |||||
Increment in R2 | 0.0316 | |||||