Table 1 Factors associated with healthcare-associated infection caused by antimicrobial resistant versus susceptible Acinetobacter baumannii in two New York City hospitals, 2006-2012
Resistant to ampicillin or ampicillin/sulbactam | |||
|---|---|---|---|
Yes, N (%) | No, N (%) | P-value* | |
Total | 302 (45 %) | 369 (55 %) | |
Mean (range) age, in years | 61 (19–98) | 61 (18–97) | 0.65 |
Sex | |||
Female | 125 (41 %) | 160 (43 %) | 0.61 |
Male | 177 (59 %) | 209 (57 %) | |
Hospital | |||
A | 217 (76 %) | 190 (58 %) | <0.0001 |
B | 70 (24 %) | 139 (42 %) | |
ICU prior to infection | |||
Yes | 219 (83 %) | 178 (82 %) | 0.72 |
No | 44 (17 %) | 39 (18 %) | |
Mean (range) Charlson Comorbidity Index | 5.61 (0–17) | 5.39 (0–16) | 0.40 |
Mean (range) days of stay prior to infection | 39 (3–377) | 18 (3–193) | <0.0001 |
High risk medication prior to infection | |||
Yes | 136 (72 %) | 155 (77 %) | 0.24 |
No | 53 (28 %) | 46 (23 %) | |
Prior stay in skilled nursing facility | |||
Yes | 21 (7 %) | 31 (8 %) | 0.49 |
No | 281 (93 %) | 338 (92 %) | |
Prior in-network hospitalization | |||
Yes | 72 (24 %) | 74 (20 %) | 0.24 |
No | 230 (76 %) | 295 (80 %) | |
Year of infection onset | |||
2006 | 32 (11 %) | 69 (19 %) | 0.003 |
2007 | 67 (22 %) | 65 (18 %) | |
2008 | 64 (21 %) | 48 (13 %) | |
2009 | 40 (13 %) | 52 (14 %) | |
2010 | 36 (12 %) | 44 (12 %) | |
2011 | 41 (14 %) | 47 (13 %) | |
2012 | 22 (7 %) | 44 (12 %) | |
Site of infection | |||
Bloodstream | 65 (22 %) | 85 (23 %) | 0.64 |
Urinary tract | 96 (32 %) | 123 (33 %) | 0.67 |
Pneumonia | 187 (62 %) | 172 (47 %) | <0.0001 |
Season of infection onset | |||
Winter | 67 (22 %) | 83 (22 %) | 0.75 |
Spring | 76 (25 %) | 95 (26 %) | |
Summer | 85 (28 %) | 113 (31 %) | |
Fall | 74 (25 %) | 78 (21 %) | |
Diabetes | |||
Yes | 100 (33 %) | 106 (29 %) | 0.22 |
No | 202 (67 %) | 263 (71 %) | |
Renal failure | |||
Yes | 181 (60 %) | 179 (49 %) | 0.003 |
No | 121 (40 %) | 190 (51 %) | |
Malignancy | |||
Yes | 69 (23 %) | 79 (21 %) | 0.65 |
No | 233 (77 %) | 290 (79 %) | |
Antibiotic use prior to infection | |||
Yes | 16 (40 %) | 20 (20 %) | 0.017 |
No | 24 (60 %) | 78 (80 %) | |