Prevalence, risk factors and molecular epidemiology of highly resistant gram negative rods in hospitalized patients in the Dutch region Kennemerland

Table 6 Multivariate logistic regression model between possible risk factors in clinical patients

	Unadjusted association		Fully adjusted model^a
Risk factor	Odds ratio (95 % CI)	P-value	Odds ratio (95 % CI)	P-value
Sex	1.29 (0.53–3.14)	0.568	1.12 (0.43–2.91)	0.823
Used antibiotics 6 months before current admission	1.34 (0.51–3.55)	0.559	0.84 (0.28–2.51)	0.756
Used antibiotics during admission	1.43 (0.59–3.45)	0.425	1.15 (0.41–3.23)	0.791
Admitted before current admission (up to 1 year)	2.25 (0.89–5.70)	0.086	2.21 (0.80–6.10)	0.126
Known HR-GNR positive in the past	7.32 (1.82–29.35)	0.005	6.54 (1.35–31.61)	0.020
Age (years)
Group 1 (0–56 years)	1 (ref)	-	1 (ref)	-
Group 2 (57–70 years)	1.30 (0.34–4.98)	0.701	0.84 (0.20–3.45)	0.806
Group 3 (71–79 years)	2.30 (0.69–7.69)	0.178	1.73 (0.49–6.15)	0.395
Group 4 (80–94 years)	0.77 (0.17–3.50)	0.730	0.60 (0.12–2.93)	0.530
Time from admission to sampling (days)
Group 1 (0–1 days)	1 (ref)	-	1 (ref)	-
Group 2 (2–3 days)	0.60 (0.15–2.38)	0.468	0.47 (0.11–2.01)	0.311
Group 3 (4–6 days)	0.64 (0.16–2.53)	0.519	0.52 (0.12–2.29)	0.385
Group 4 (7–48 days)	1.40 (0.49–3.98)	0.531	1.10 (0.34–3.62)	0.870

^aCorrected for (1) Antibiotic use during current admission, (2) Antibiotic use up 6 months before current admission, (3) sex, (4) age, (5) admitted before current admission, (6) time from start admission to sampling and (7) known HR-GNR positive in the past

ISSN: 2047-2994