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Table 1 Baseline characteristics of patients infected by Enterobacteriaceae producer of ESBL (ESBL+) and Enterobacteriaceae non-producer of ESBL (ESBL-)

From: Infections caused by extended-spectrum beta-lactamases producing Enterobacteriaceae: clinical and economic impact in patients hospitalized in 2 teaching hospitals in Dakar, Senegal

Variable, n (%) ESBL+ infections (n = 110) ESBL- infections (n = 76) P-value
Demographics    
 Male gender 68(61.8) 35(46.05) 0.037
 Mean age, years (range) 26.3(20.9–31.7) 28.1(21.5–34.7) 0.665
 Newborns (0–28 days) 22(20.0) 4(5.3) 0.005
 Premature babies 12(10.9) 2(2.6) 0.046
 Children (1 month-17 years) 37(33.6) 34(44.7) 0.167
 Adults (up to 17 years) 51(46.4) 38(50.0) 0.656
Comorbidity    
 Sickle cell disease 10(9.1) 7(9.2) 1
 Malnutrition 10(9.1) 7(9.2) 1
 AIDS 8(7.2) 2(2.6) 0.203
Diagnostic at admission    
 Severe malaria 19(17.3) 7(9.2) 0.808
 Gastroenteritis 16(14.5) 9(11.8) 0.666
 Respiratory disease 25(22.7) 10(9.1) 0.127
 Neurologic disorder 20(18.2) 12(15.8) 0.698
 Meningitis 10(9.1) 5(4.5) 0.596
 Tuberculosis 3(2.7) 3(3.9) 0.689
 Cancer 10(9.1) 6(7.9) 1
 Tetanus 4(3.6) 6(7.9) 0.321
Invasive procedure    
 Surgical intervention 18(16.4) 18(23.7) 0.258
 Parental nutrition 24(21.8) 6(7.9) 0.014
 Mechanical ventilation 38(34.5) 7(9.2) <0.0001
 Central venous catheter 84(76.4) 35(46.0) <0.0001
 Urinary catheter 37(33.6) 13(17.1) 0.018
Type of infection    
 Bloodstream infection 49(44.5) 20(26.3) 0.013
 Urinary tract infection 36(32.7) 31(40.8) 0.279
 Surgical site infection 13(11.8) 11(14.4) 0.656
 Respiratory infection 5(4.5) 12(15.8) 0.016
 Meningitidis 7(6.4) 2(2.6) 0.313
Time to infection, in days (95%CI)    
 All patients 8.2(6.4–9.9) 4.8(2.7–6.9) 0.007
 Adults 11.3(8.8–13.8) 7.7(4.8–10.6) 0.029
 Children 6.6(3.1–10.2) 2(1.2–5.2) 0.028
 Newborns 3.5(2.2–4.8) 1(0.3–2.3) 0.059
Mean time after infection, days (95 % CI)    
 All patients 14.2(12.6–16.3) 9.3(7.4–11.1) <0.0001
 Adults 15.1(11.9–18.3) 8.9(7.2–10.6) 0.001
 Children 15.5(12.3–18.7) 10(6.3–13.7) 0.013
 Newborns 11.1(8.7–13.5) 6.2(5.8–13.0) 0.050
 Inadequate antibiotherapy prescription 97(88.2) 14(18.4) <0.0001