Table 2 Risk factors for fatal outcomes: results of univariate and multivariable analyses

Demographics

 Male gender

34(49.3)

49(41.9)

1.3

0.7–2.4

0.361

 Mean age, years (range)

27.1(20.4–33.8)

26.9(21.6–32.3)

0.489

 Newborns (0–28 days)

16(23.2)

10(8.5)

3.2

1.4–7.5

0.008

4.5

2.4–37.8

0.025

P remature babies

9(13.0)

5(4.3)

3.4

1.1–9.9

0.042

 Children (1 month–17 years)

17(24.6)

54(46.1)

2.6

1.4–5.0

0.005

 Adults (up to 17 years)

36(52.2)

53(45.3)

1.3

0.7–2.4

0.448

Comorbidity

 Sickle cell disease

6(8.7)

11(0.5)

0.5

0.3–2.5

1

 Malnutrition

4(5.8)

13(11.1)

0.5

0.5–1.5

0.296

 AIDS

3(4.3)

7(5.9)

0.7

0.2–2.6

0.747

Diagnostic at admission

 Gastroenteritis

6(8.7)

19(16.2)

0.5

0.2–1.3

0.184

 Respiratory disease

18(26.1)

17(14.5)

2.1

0.9–4.3

0.079

 Meningitis

11(15.9)

4(3.4)

5.3

1.7–16.6

0.004

2.3

1.5–4.9

<0.0001

 Tuberculosis

2(2.8)

4(3.4)

0.8

0–4.1

1

 Cancer

12(20.3)

4(3.4)

5.9

1.9–18.3

0.002

2.7

1.6–6.6

0.001

 Neurologic disorder

8(11.5)

24(20.5)

0.5

0.2–1.2

0.159

Invasive procedure

 Surgical intervention

15(21.7)

21(17.9)

1.3

0.6–2.6

0.567

 Parenteral nutrition

15(21.7)

15(12.8)

1.9

0.9–4.1

0.148

 Mechanical ventilation

28(40.5)

17(14.5)

3.9

1.9–7.9

0.0002

6.1

3.1–124.6

0.040

 Central venous catheter

53(76.8)

66(56.4)

2.6

1.3–4.9

0.007

 Urinary catheter

14(20.3)

36(30.8)

0.6

0.3–1.1

0.128

 ESBL Production

52(75.4)

58(49.6)

3.1

1.6–5.9

<0.0001

5.3

3.1–19.9

0.008

Type of infection

 Bloodstream infection

31(44.9)

38(32.5)

1.7

0.9–3.1

0.116

 Urinary tract infection

18(26.1)

49(41.9)

0.5

0.2–0.9

0.039

 Meningitidis

7(10.1)

2(1.7)

6.5

1.5–25.7

0.014

 Surgical site infection

9(13.0)

15(12.8)

1.0

0.4–2.4

1

 Respiratory infection

4(6.8)

8(7.7)

0.8

0.2–2.7

1

 Inadequate antibiotherapy prescription

49(71.0)

62(52.9)

2.3

1.2–4.3

0.013

 Mean time to infection, days, (95 % CI)

5.9(4.3–7.5)

7.3(5.4–9.3)

0.838