Patient no. | Sex (age [yr]) | Underlying Disease | Allogeneic HSCT | Localisation of LVRE (except bloodstream) | Bloodstream infection with LVRE | Previous linezolid exoposure | Clinical outcome | Previous hospital | MICs (mg/L) of the nine further characterized LVRE isolate | PFGE type | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Linezolid | Vancomycin | Teicoplanin | Daptomycin | ||||||||||
1 | M (66) | lymphoma | yes | rectal | no | yes | death | A | – | – | – | – | – |
2 | M (64) | arthritis-metothrexat | no | urine | no | yes | discharge | unknown | – | – | – | – | – |
3 | F (34) | acute myeloic leukemia | yes | rectal, inguinal | yes | yes | death | C | – | – | – | – | – |
4 | F (47) | acute myeloic leukemia | yes | rectal, urine | no | unknwon | discharge | D | – | – | – | – | – |
5 | M (70) | acute myeloic leukemia | yes | rectal | yes | yes | discharge | E | – | – | – | – | – |
6 | F (54) | acute myeloic leukemia | yes | rectal, oral cavity, BAL | no | unknown | death | D | – | – | – | – | – |
7 | F (48) | myelodysplastic syndrome | yes | rectal, inguinal, wound | yes | yes | death | C | 16 | 512 | 64 | 2 | II |
8 | F (67) | acute lymphatic leukemia | yes | anal, inguinal, oral cavity | yes | unknown | discharge in palliative care | D | – | – | – | – | – |
9 | F (70) | myelodysplastic syndrome | yes | rectal, armpit, urine | no | yes | discharge | D | >32 | 512 | 128 | 2 | I |
10 | F (68) | aplastic anemia | yes | urine | no | unknown | death | D | – | – | – | – | – |
11 | F (20) | acute myeloic leukemia | yes | urine | no | unknown | discharge | D | – | – | – | – | – |
12 | M (58) | myelodysplastic syndrome | yes | rectal, inguinal | no | unknown | discharge | D | 32 | 512 | 128 | 2 | I |
13 | F (58) | acute myeloic leukemia | yes | rectal, urine | no | unknown | discharge | D | 16 | 512 | 128 | 2 | I |
14 | M (53) | acute myeloic leukemia | yes | rectal, hair | yes | no | discharge | D | 16 | 512 | 128 | 4 | I |
15 | F (10) | histiocytosis | yes | rectal, urine | no | unknown | discharge | F | – | – | – | – | – |
16 | F (22) | acute myeloic leukemia | yes | rectal | no | no | discharge | D | 16 | 512 | 128 | 2 | I |
17 | M (62) | acute myeloic leukemia | yes | rectal, oral cavity | no | unknown | discharge | D | 16 | 512 | 128 | 2 | I |
18 | M (57) | acute myeloic leukemia | yes | rectal, urine | no | unknown | death | D | – | – | – | – | – |
19 | F (70) | acute myeloic leukemia | yes | rectal, oral cavity, urine | no | yes | discharge | G | 32 | 512 | 128 | 2 | IV |
20 | M (54) | multiple myeloma | no | rectal | no | yes | Discharge in palliative care | H | 16 | 1024 | <1 | 2 | III |