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Table 1 MICs of six antibiotics (in mg/L); alone or in combination with a β-lactamase inhibitor

From: Effect of β-Lactamase inhibitors on in vitro activity of β-Lactam antibiotics against Burkholderia cepacia complex species

  1. Bold values indicate combinations leading to at least 4-fold MIC-reduction upon addition of the β-lactamase inhibitor. Underlined values indicate a shift from resistant to susceptible upon addition of the β-lactamase inhibitor, according to PK/PD (non-species related) EUCAST breakpoints. [22] “-“represents treatment with β-lactam antibiotic alone. CAZ ceftazidime, MEM meropenem, AMOX amoxicillin, CFX cefoxitin, CFP cefepime, AZT aztreonam. Cla clavulanic acid, Sul sulbactam, Taz tazobactam, Avi avibactam
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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