Patterns of medication use and factors associated with antibiotic use among adult fever patients at Singapore primary care clinics

Table 3 Subgroup Analysis of Patients Who Met the Influenza-like Illness definition [12] at Polyclinics, December 2007-February 2013

Characteristics	Unadjusted OR (95% CI)	p value	Adjusted OR (95% CI)	p value
Age (years)^a
17–24	1	0.6777	1	0.9438
25–34	0.77 (0.46–1.28)		0.84 (0.48–1.49)
35–44	0.96 (0.55–1.70)		0.94 (0.50–1.77)
45–54	0.89 (0.50–1.60)		0.79 (0.41–1.51)
55–64	1.24 (0.69–2.25)		1.11 (0.56–2.17)
65 and above	1.25 (0.55–2.87)		0.92 (0.37–2.34)
Gender^a
Female	1	0.0147	1	0.1394
Male	0.64 (0.44–0.91)	0.0147	0.72 (0.47–1.11)	0.1394
Year of enrolment^a
Dec 2007–2008	1	0.0021	1	0.0239
2009	0.91 (0.29–2.84)		1.45 (0.42–4.94)
2010	0.37 (0.13–1.12)		0.62 (0.19–1.97)
2011	0.90 (0.31–2.64)		1.20 (0.39–3.71)
2012-Feb 2013	0.56 (0.19–1.68)		0.68 (0.22–2.15)
Polyclinic enrolled^a
Polyclinic A	1	<0.0001	1	<0.0001
Polyclinic B	0.22 (0.14–0.37)		0.24 (0.14–0.41)
Polyclinic C	0.39 (0.2–0.77)		0.31 (0.14–0.67)
Polyclinic D and E^b	0.76 (0.21–2.82)		0.61 (0.15–2.46)
Number of initial visit symptom persisting at first follow-up
0	1	<0.0001	1	<0.0001
1	1.68 (0.96–2.93)		1.42 (0.79–2.57)
2	2.48 (1.38–4.45)		2.30 (1.23–4.30)
3	6.55 (3.59–11.94)		5.12 (2.67–9.83)
4 and above	2.37 (1.34–4.17)		2.28 (1.24–4.19)
WBC count at initial visit (cells/μL)
Leukopenia (<4)	1.07 (0.57–2.04)		0.99 (0.49–2.01)
Normal range (4–11)	1	0.1440	1	0.0433
Leukocytosis (>11)	1.61 (1.01–2.55)		1.97 (1.17–3.33)

OR odds ratio
^aVariables included a priori as covariates in the model
^bPolyclinic D and E were combined because of low number of patients (5 and 8 respectively)

ISSN: 2047-2994