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Table 2 Systematic reviews about the association between oral care and reduction in pneumonia or respiratory tract infection

From: Prevention of hospital-acquired pneumonia in non-ventilated adult patients: a narrative review

Author, journal, date

Type of studies included

Population

Type of intervention

Major conclusion

Azarpazhooh A. et al., J Periodontol, 2006 [37]

Systematic Review (7 RCT, 3 control trials)

Elderly adults living in nursing homes, ICU patients and patients from a general hospital

Professional dental care, mouthrinse with 0.12 % CHX, application of 0.2% CHX gel, 1% PVI scrubbing of pharynx, topical application of a non-absorbable antibiotic solution and topical antimicrobial prophylaxis

Oral care reduces incidence of pneumonia

Sjorgen P. et al., J Am Geriatr Soc, 2008 [36]

Systematic Review (5 RCT, 1 systematic review, 3 case–control trials, 5 cross-sectional trials, 1 retrospective trial)

Dependent elderly people

0.12% CHX oral rinse, tooth-brushing, 1% PVI scrubbing of pharynx or professional mechanical oral health care weekly

Oral care prevents pneumonia, respiratory tract infection and death from pneumonia

Kaneoka A. et al., Infect Control Hosp Epidemiol, 2015 [34]

Systematic Review (4 RCT) and Meta-analysis (5 RCT)

Hospitalized non-ventilated patients and patients living in nursing homes

0.2% CHX application, 0.12% CHX gargle, tooth brushing performed by dental professionals, ± 1% PVI scrubbing of pharynx

Oral care prevents pneumonia and fatal pneumonia in non-ventilated patients

El-Rabbany M. et al., Int J Nurs Stud, 2015 [35]

Systematic Review (28 RCT)

Elderly adults living in nursing homes and ICU patients

Professional dental care, sodium bicarbonate mouthrinse, toothbrushing, 0.12% and 0.2% CHX, topical application of a non-absorbable antibiotic solution and PVI swab

Oral care was suggested to be associated with a reduction in the risk for HAP and VAP in high-risk patients

  1. CHX chlorhexidine, HAP hospital-acquired pneumonia, ICU Intensive Care Unit, PVI povidone-iodine, RCT Randomized Control Trials, VAP ventilator-associated pneumonia