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Table 5 Susceptibility of isolates to quinolone drugs and mutation in QRDR

From: Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidal Salmonella isolates from humans and animals in central Ethiopia

 

Serotype

Zone of inhibition mm (susceptibility category)

R-pattern betalactamsa

Mutation in QRDR

Na

Cip

 

gyrA

gyrB

parC

Cattle

Aberdeen

19[S]

27[I]

-

-

-

-

Cattle

Virchow

20[S]

25[I]

-

-

-

-

Cattle

Typhimurium PT 3

21[S]

25[I]

AmpAmcCf

-

-

-

Cattle

Typhimurium PT 4

22[S]

27[I]

AmpAmcCf

-

-

-

Cattle

Haifa

21[S]

25[I]

-

-

-

-

Poultry

Saintpaul

20[S]

31[S]

AmcCf

-

-

-

Cattle

Saintpaul

17[I]

25[I]

AmpAmcCCf

-

-

-

Cattle

Saintpaul

21[S]

27[I]

-

-

-

-

Poultry

Saintpaul

20[S]

27[I]

-

-

-

-

Human

V:ROUGH-O;-:-

22[S]

28[I]

AmpCf

-

Ser463Ala

-

Cattle

Mikawasima

20[S]

25[I]

-

-

Val423Gly + Asp459His

-

Cattle

Agona

17[I]

31[S]

-

-

-

Thr57Ser

Cattle

Braenderup

17[I]

25[I]

-

-

Val423Gly + Asp459His

Thr57Ser

Swine

Miami

22[S]

27[I]

-

-

-

Thr57Ser + Tyr83Phe

Poultry

Haifa

0[R]

25[I]

-

Ser83Tyr

-

-

Cattle

Virchow

0[R]

26(I)

AmpAmcCf

Ser83Phe

-

-

Cattle

Livingstone var.14+

0[R]

24(I)

-

Ser83Phe

-

-

Cattle

I:6;7,14:-:I,w

7[R]

30(I)

AmpAmcCf

Ser83Phe

-

-

Swine

Livingstone var.14+

0[R]

20[I]

-

Ser83Phe

-

-

Cattle

Kentucky

0[R]

14[R]

AmpAmcCf

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Cattle

Kentucky

0[R]

12[R]

AmpCf Amc

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Cattle

Kentucky

0[R]

11[R]

AmpCf Amc

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Cattle

Kentucky

0[R]

9[R]

AmpAmcCf

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Cattle

Kentucky

0[R]

12[R]

AmpCf Amc

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Cattle

Kentucky

0[R]

10[R]

AmpAmcCf

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Human

Kentucky

0[R]

8[R]

AmpAmcCf Fox

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Human

Kentucky

0[R]

10[R]

AmpCf Amc

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Poultry

Kentucky

0[R]

9[R]

AmpAmcCf

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

Poultry

Kentucky

0[R]

11[R]

AmpAmcCf

Ser83Phe + Asp87Gly

-

Thr57Ser + Ser80Ile

  1. PT Phagetype, Amp Ampicillin, Amc Amoxicillin and clavulanic acid, Cf Cephalothin, Cip Ciprofloxacin, Na- Nalidixic acid, S susceptible, I intermediately resistant, R resistant
  2. aResistance status, isolates were fully resistant to antimicrobials written in Bold and intermediately resistant to those written in italics