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Table 5 Susceptibility of isolates to quinolone drugs and mutation in QRDR

From: Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidal Salmonella isolates from humans and animals in central Ethiopia

  Serotype Zone of inhibition mm (susceptibility category) R-pattern betalactamsa Mutation in QRDR
Na Cip   gyrA gyrB parC
Cattle Aberdeen 19[S] 27[I] - - - -
Cattle Virchow 20[S] 25[I] - - - -
Cattle Typhimurium PT 3 21[S] 25[I] AmpAmcCf - - -
Cattle Typhimurium PT 4 22[S] 27[I] AmpAmcCf - - -
Cattle Haifa 21[S] 25[I] - - - -
Poultry Saintpaul 20[S] 31[S] AmcCf - - -
Cattle Saintpaul 17[I] 25[I] AmpAmcCCf - - -
Cattle Saintpaul 21[S] 27[I] - - - -
Poultry Saintpaul 20[S] 27[I] - - - -
Human V:ROUGH-O;-:- 22[S] 28[I] AmpCf - Ser463Ala -
Cattle Mikawasima 20[S] 25[I] - - Val423Gly + Asp459His -
Cattle Agona 17[I] 31[S] - - - Thr57Ser
Cattle Braenderup 17[I] 25[I] - - Val423Gly + Asp459His Thr57Ser
Swine Miami 22[S] 27[I] - - - Thr57Ser + Tyr83Phe
Poultry Haifa 0[R] 25[I] - Ser83Tyr - -
Cattle Virchow 0[R] 26(I) AmpAmcCf Ser83Phe - -
Cattle Livingstone var.14+ 0[R] 24(I) - Ser83Phe - -
Cattle I:6;7,14:-:I,w 7[R] 30(I) AmpAmcCf Ser83Phe - -
Swine Livingstone var.14+ 0[R] 20[I] - Ser83Phe - -
Cattle Kentucky 0[R] 14[R] AmpAmcCf Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Cattle Kentucky 0[R] 12[R] AmpCf Amc Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Cattle Kentucky 0[R] 11[R] AmpCf Amc Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Cattle Kentucky 0[R] 9[R] AmpAmcCf Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Cattle Kentucky 0[R] 12[R] AmpCf Amc Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Cattle Kentucky 0[R] 10[R] AmpAmcCf Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Human Kentucky 0[R] 8[R] AmpAmcCf Fox Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Human Kentucky 0[R] 10[R] AmpCf Amc Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Poultry Kentucky 0[R] 9[R] AmpAmcCf Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
Poultry Kentucky 0[R] 11[R] AmpAmcCf Ser83Phe + Asp87Gly - Thr57Ser + Ser80Ile
  1. PT Phagetype, Amp Ampicillin, Amc Amoxicillin and clavulanic acid, Cf Cephalothin, Cip Ciprofloxacin, Na- Nalidixic acid, S susceptible, I intermediately resistant, R resistant
  2. aResistance status, isolates were fully resistant to antimicrobials written in Bold and intermediately resistant to those written in italics