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Table 3 Univariate and multivariate logistic regression of the effects of clinical variables on relapsed Enterobacter bacteraemia

From: Risk factors for relapse or persistence of bacteraemia caused by Enterobacter spp.: a case–control study

Variable Cases (relapse)
N = 31
Controls
(non-relapse)
N = 128
Univariate model Multivariate model
OR 95% CI P OR 95% CI P
Age, mean (SD) 52.0 (17.0) 60.5 (18.6) 0.98 0.95-1.00 0.02*    
 Sex Female 16 (51.6%) 49 (38.3%) female as reference
Male 15 (48.4%) 79 (61.7%) 0.58 0.26-1.28 0.18    
 Medical Service Med/surg 10 (32.3%) 82 (64.1%) general medical / surgical as reference
Haem/onc 15 (48.4%) 30 (23.4%) 4.1 1.66-10.11 0.002*    
Renal 6 (19.4%) 16 (12.5%) 3.08 0.98-9.66 0.06    
 Definitive therapy Standard 23 (74.2%) 105 (82.0%) carbapenem, quinolone, cefepime, aminoglycoside or co-trimoxazole as reference
BLBLI 6 (19.4%) 15 (11.7%) 1.83 0.64-5.21 0.26    
Inappropriate 2 (6.5%) 8 (6.2%) 1.14 0.23-5.73 0.87    
 Source Non-line source 8 (25.8%) 80 (62.5%) non-line source as reference
Line-associated 23 (74.2%) 48 (37.5%) 4.79 1.99-11.56 <0.001* 3.87 1.56-9.60 0.004*
 Immune
 suppression
Absent 12 (38.7%) 83 (64.8%) no immunosuppression as reference
Present 19 (61.3%) 45 (35.2%) 2.92 1.30-6.56 0.009* 2.70 1.14-6.44 0.02*
 ICU admission Non-ICU 25 (80.6%) 99 (78.6%) non-ICU admitted as reference
ICU 6 (19.4%) 27 (21.4%) 0.88 0.33-2.36 0.80    
 Acquisition status Community 2 (6.5%) 29 (22.7%) community-associated infection as reference
Healthcare 29 (93.5%) 99 (77.3%) 4.25 0.96-18.87 0.06    
 Region NSW 15 (48.4%) 73 (57.0%) New South Wales region as reference
Queensland 16 (51.6%) 55 (43.0%) 1.42 0.64-3.11 0.39    
De-repressed AmpC phenotype Absent 22 (71.0%) 76 (59.4%) no de-repressed AmpC as reference
Present 9 (29.0%) 52 (40.6%) 0.60 0.26-1.40 0.24    
SAPS II score, mean (SD) 37.9 (15.9) 33.9 (12.9) 1.02 0.99-1.05 0.14    
 Enterobacter species Other Enterobacter spp. 6 (19.4%) 31 (24.2%) other Enterobacter spp. as reference
E. cloacae 25 (80.6%) 97 (75.8%) 1.33 0.50-3.54 0.57    
  1. *significant p < 0.05