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Table 3 Univariate and multivariate logistic regression of the effects of clinical variables on relapsed Enterobacter bacteraemia

From: Risk factors for relapse or persistence of bacteraemia caused by Enterobacter spp.: a case–control study

Variable

Cases (relapse)

N = 31

Controls

(non-relapse)

N = 128

Univariate model

Multivariate model

OR

95% CI

P

OR

95% CI

P

Age, mean (SD)

52.0 (17.0)

60.5 (18.6)

0.98

0.95-1.00

0.02*

   

 Sex

Female

16 (51.6%)

49 (38.3%)

female as reference

Male

15 (48.4%)

79 (61.7%)

0.58

0.26-1.28

0.18

   

 Medical Service

Med/surg

10 (32.3%)

82 (64.1%)

general medical / surgical as reference

Haem/onc

15 (48.4%)

30 (23.4%)

4.1

1.66-10.11

0.002*

   

Renal

6 (19.4%)

16 (12.5%)

3.08

0.98-9.66

0.06

   

 Definitive therapy

Standard

23 (74.2%)

105 (82.0%)

carbapenem, quinolone, cefepime, aminoglycoside or co-trimoxazole as reference

BLBLI

6 (19.4%)

15 (11.7%)

1.83

0.64-5.21

0.26

   

Inappropriate

2 (6.5%)

8 (6.2%)

1.14

0.23-5.73

0.87

   

 Source

Non-line source

8 (25.8%)

80 (62.5%)

non-line source as reference

Line-associated

23 (74.2%)

48 (37.5%)

4.79

1.99-11.56

<0.001*

3.87

1.56-9.60

0.004*

 Immune

 suppression

Absent

12 (38.7%)

83 (64.8%)

no immunosuppression as reference

Present

19 (61.3%)

45 (35.2%)

2.92

1.30-6.56

0.009*

2.70

1.14-6.44

0.02*

 ICU admission

Non-ICU

25 (80.6%)

99 (78.6%)

non-ICU admitted as reference

ICU

6 (19.4%)

27 (21.4%)

0.88

0.33-2.36

0.80

   

 Acquisition status

Community

2 (6.5%)

29 (22.7%)

community-associated infection as reference

Healthcare

29 (93.5%)

99 (77.3%)

4.25

0.96-18.87

0.06

   

 Region

NSW

15 (48.4%)

73 (57.0%)

New South Wales region as reference

Queensland

16 (51.6%)

55 (43.0%)

1.42

0.64-3.11

0.39

   

De-repressed AmpC phenotype

Absent

22 (71.0%)

76 (59.4%)

no de-repressed AmpC as reference

Present

9 (29.0%)

52 (40.6%)

0.60

0.26-1.40

0.24

   

SAPS II score, mean (SD)

37.9 (15.9)

33.9 (12.9)

1.02

0.99-1.05

0.14

   

 Enterobacter species

Other Enterobacter spp.

6 (19.4%)

31 (24.2%)

other Enterobacter spp. as reference

E. cloacae

25 (80.6%)

97 (75.8%)

1.33

0.50-3.54

0.57

   
  1. *significant p < 0.05
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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