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Table 3 Susceptibility profiles for selected Gram-positive species, S. aureus (a) and S. pneumoniae (b)

From: Retrospective report of antimicrobial susceptibility observed in bacterial pathogens isolated from ocular samples at Mount Sinai Hospital, 2010 to 2015

3a: Susceptibility Profile for 113 S. aureus isolates

Antimicrobial

 

MIC (ug/mL)

Interpretation N (%)

 

Organism

Range

MIC50

MIC90

Susceptible

Intermediate

Resistant

 Clindamycin

MRSA

0.25 – ≥8

0.25

≥8

18 (64.3)

0 (0)

10 (35.7)

MSSA

≤0.12 – ≥8

0.25

<0.5

56 (65.9)

0 (0)

29 (34.1)

 Ciprofloxacin*

MRSA

≤0.5 – ≥8

≥8

≥8

5 (20)

0 (0)

20 (80)

MSSA

≤0.5 – ≥8

≤0.5

≤0.5

74 (91.4)

1 (1.2)

6 (7.4)

 Daptomycin

MRSA

0.25 – 1

0.5

1

28 (100)

0 (0)

0 (0)

MSSA

≤0.12 – 1

0.25

0.5

85 (100)

0 (0)

0 (0)

 Erythromycin

MRSA

≤0.25 – ≥8

≥8

≥8

3 (10.7)

0 (0)

25 (89.3)

MSSA

≤0.25 – ≥8

0.5

≥8

47 (56)

0 (0)

37 (44)

 Gentamicin

MRSA

≤0.5 – ≥16

≤0.5

8

24 (85.7)

2 (7.1)

2 (7.1)

MSSA

≤0.5 – 4

≤0.5

≤0.5

85 (100)

0 (0)

0 (0)

 Levofloxacin

MRSA

0.25 – ≥8

4

≥8

6 (21.4)

8 (28.6)

14 (50)

MSSA

≤0.12 – ≥8

0.25

2

80 (94.1)

2 (2.4)

3 (3.5)

 Linezolid

MRSA

2 – 4

2

2

28 (100)

0 (0)

0 (0)

MSSA

1 – 4

2

2

85 (100)

0 (0)

0 (0)

 Trimethoprim/Sulfamethoxazole

MRSA

≤0.5 – ≥16

≤0.5

8

25 (89.3)

0 (0)

3 (10.7)

MSSA

≤0.5 – ≥16

0.5

0.5

84 (98.8)

0 (0)

1 (1.2)

 Tetracycline*

MRSA

≤1 – ≥16

≤1

4

22 (91.7)

0 (0)

2 (8.3)

MSSA

≤1 – ≥16

≤1

4

48 (94.1)

0 (0)

3 (5.9)

 Vancomycin

MRSA

≤0.5 – 2

1

2

28 (100)

0 (0)

0 (0)

MSSA

≤0.5 – 2

1

1

37 (100)

0 (0)

0 (0)

3b: Susceptibility Profile for 30 S. pneumoniae isolates

Antimicrobial

MIC (ug/mL)

Interpretation N (%)

  

Range

MIC50

MIC90

Susceptible

Intermediate

Resistant

 Ceftriaxone (non-meningitis)#

 

.004 – 0.5

0.032

0.25

23 (100)

0 (0)

0 (0)

 Clindamycin#

 

.032 – 1

0.125

0.25

27(93.2)

1 (3.4)

1 (3.4)

 Erythromycin

 

.016 – 32

0.25

2

22 (73.3)

3 (10)

5 (16.7)

 Levofloxacin

 

0.25 – 4

1

1

29 (96.7)

0 (0)

1 (3.3)

 Penicillin (non-meningitis)#

 

.008 – 2

0.032

0.5

25 (100)

0 (0)

0 (0)

 Vancomycin

 

.25 – 2

0.5

1

29 (96.7)

0 (0)

1 (3.3)

  1. *Antimicrobials that were not tested against all 28 MRSA isolates
  2. #Antimicrobials that were not tested against 30 or more S. pneumoniae isolates
  3. Abbreviations: MSSA = methicillin-susceptible Staphylococcus aureus, MRSA = methicillin-resistant Staphylococcus aureus, MIC = minimum inhibitory concentration (at 50% and 90%)