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Table 1 Immediate bactericidal effects of the modified WHO-formulation II and TPH 5766 as compared to that of the reference hand rub for pre-surgical hand antisepsis according to EN 12791

From: Influence of glycerol and an alternative humectant on the immediate and 3-hours bactericidal efficacies of two isopropanol-based antiseptics in laboratory experiments in vivo according to EN 12791

Formulation

duration of application

(n × 3 ml)

Mean (n = 20)

log10 pre-value

Mean (n = 20)

log10 reduction

p-value for difference to reference

Reference

3 min

4.46 ± 0.63

2.56 ± 1.10

 

WHO II-modified

3 min

4.36 ± 0.52

2.22 ± 1.15

0.176

WHO II-modified

5 min

4.45 ± 0.44

2.65 ± 1.03

0.731

TPH 5766

3 min

4.41 ± 0.64

2.53 ± 1.20

0.887

TPH 5766

5 min

4.37 ± 0.52

2.75 ± 1.25

0.513

  1. P < 0.1, one-sided (ANOVA, linear contrasts)