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Table 1 Immediate bactericidal effects of the modified WHO-formulation II and TPH 5766 as compared to that of the reference hand rub for pre-surgical hand antisepsis according to EN 12791

From: Influence of glycerol and an alternative humectant on the immediate and 3-hours bactericidal efficacies of two isopropanol-based antiseptics in laboratory experiments in vivo according to EN 12791

Formulation duration of application
(n × 3 ml)
Mean (n = 20)
log10 pre-value
Mean (n = 20)
log10 reduction
p-value for difference to reference
Reference 3 min 4.46 ± 0.63 2.56 ± 1.10  
WHO II-modified 3 min 4.36 ± 0.52 2.22 ± 1.15 0.176
WHO II-modified 5 min 4.45 ± 0.44 2.65 ± 1.03 0.731
TPH 5766 3 min 4.41 ± 0.64 2.53 ± 1.20 0.887
TPH 5766 5 min 4.37 ± 0.52 2.75 ± 1.25 0.513
  1. P < 0.1, one-sided (ANOVA, linear contrasts)