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Table 2 Change in percentage of iv antibiotic prescriptions >72 h and median antibiotic duration (days) during the pre-intervention and post-intervention period and comparison between the intervention and control group using interrupted time series analysis

From: An electronic trigger tool to optimise intravenous to oral antibiotic switch: a controlled, interrupted time series study

 

Slope during the pre-intervention period (SE)

P

Change in level after interventiona (SE)

P

Slope during the post-intervention periodb (SE)

P

Percentage of iv antibiotic prescriptions >72 h (%)

 Intervention group

−0.03 (0.42)

0.94

−19.30 (4.41)

<0.01

0.48 (0.59)

0.43

 Control group

−0.36 (0.25)

0.16

−6.12 (2.61)

<0.05

−0.26 (0.35)

0.46

 Difference between intervention and control group

0.33 (0.48)

0.50

−13.17 (5.13)

<0.05

0.74 (0.68)

0.29

Median duration of iv antibiotics (days)

 Intervention group

−0.02 (0.03)

0.49

−0.77 (0.29)

0.015

0.02 (0.04)

0.63

 Control group

−0.38 (0.03)

0.16

−0.15 (0.28)

0.59

0.04 (0.04)

0.32

 Difference between intervention and control group

0.02 (0.04)

0.62

0.62 (0.41)

0.14

−0.02 (0.05)

0.72

  1. aMeasures the immediate impact of the intervention
  2. bMeasures the long-term impact over time of the intervention