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Table 2 Mutations in gyrA, gyrB and parC genes in Shigella flexneri strains in the present study

From: Newest data on fluoroquinolone resistance mechanism of Shigella flexneri isolates in Jiangsu Province of China

Mutations 2012 (n = 120) 2013 (n = 114) 2014 (n = 85) 2015 (n = 81) Total (n = 400)
Ser83Leu 79.2 (95) 75.4 (86) 75.3 (64) 70.4 (57) 75.5 (302)
Asp87Asn/ Gly 65.0 (78) 50.9 (58) 61.2 (52) 50.6 (41) 57.3 (229)
Asp87Asn 24.2 (29) 24.6 (28) 41.2 (35) 37.0 (30) 30.5 (122)
Asp87 Gly 40.8 (49) 26.3 (30) 20.1 (17) 13.6 (11) 26.8 (107)
His211Tyr 75.0 (90) 74.6 (85) 75.3 (64) 69.1 (56) 73.8 (295)
Gln517Arg 5.8 (7) 3.5 (4) 2.5 (2) 0.0 (0) 3.3 (13)
Ser80Ile 77.5 (93) 75.4 (86) 75.3 (64) 67.9 (55) 74.5 (298)
Ser129Pro 33.3 (40) 41.2 (47) 52.9 (45) 24.7 (20) 38.0 (152)