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Table 4 The Asp-87 mutation in gyrA in the four predominate Shigella flexneri serotypes

From: Newest data on fluoroquinolone resistance mechanism of Shigella flexneri isolates in Jiangsu Province of China

Serotypes Mutation Years Total
2012 (%a) 2013 (%b) 2014 (%c) 2015 (%d)
2a (n = 156) gyrA-Asp87Asn 59.6 (28/47) 53.7 (22/41) 63.6 (21/33) 82.9 (29/35) 64.1 (100/156)
gyrA-Asp87Gly 23.4 (11/47) 9.8 (4/41) 15.2 (5/33) 14.3 (5/35) 16.0 (25/156)
1a (n = 75) gyrA-Asp87Asn 0.0 (0/25) 10.7 (3/28) 53.8 (7/13) 0.0 (0/9) 13.3 (10/75)
gyrA-Asp87Gly 88.0 (22/25) 39.3 (11/28) 23.1 (3/13) 33.3 (3/9) 52.0 (39/75)
2b (n = 66) gyrA-Asp87Asn 0.0 (0/21) 10.5 (2/19) 8.3 (1/12) 7.1 (1/14) 6.1 (4/66)
gyrA-Asp87Gly 76.2 (16/21) 68.4 (13/19) 58.3 (7/12) 21.4 (3/14) 59.1 (39/66)
1b (n = 61) gyrA-Asp87Asn 0.0 (0/20) 0.0 (0/10) 0.0 (0/12) 0.0 (0/19) 0.0 (0/61)
gyrA-Asp87Gly 0.0 (0/20) 0.0 (0/10) 0.0 (0/12) 0.0 (0/19) 0.0 (0/61)
  1. a% = Mutation strains/number of different serotypes in 2012
  2. b% = Mutation strains/number of different serotypes in 2013
  3. c% = Mutation strains/number of different serotypes in 2014
  4. d% = Mutation strains/number of different serotypes in 2015