Table 6 Antimicrobial spectrum and amino acid types in QRDR and PMQRs genes analysis of S. flexneri 2a with resistance to fluoroquinolones
Strain name | Antimicrobial spectrum | QRDR | ARGs in plasmid | ||||
|---|---|---|---|---|---|---|---|
gyrA | parC | aac(6′)-Ib-cr | qnrS | qepA | |||
83 | 87 | 80 | |||||
GBSF1509369 | NOR/LEV | S83 L | D87N | S80I | + | − | − |
GBSF1511401 | NOR/LEV | S83 L | D87N | S80I | + | − | − |
GBSF1608241 | NOR/LEV | S83 L | D87N | S80I | + | − | − |
GBSF1510390 | ENR/LEV | S83 L | D87D | S80I | + | + | − |
GBSF1603138 | ENR/LEV | S83 L | D87N | S80I | + | − | − |
GBSF1603149 | ENR/LEV | S83 L | D87N | S80I | + | − | − |
GBSF1505314 | NOR/ENR/LEV/CIP | S83 L | D87Y | S80I | + | + | − |
GBSF1601064 | KF/KZ/MA/CRO/CTX/NOR/LEV | S83 L | D87N | S80I | + | − | − |
SBSF1604173 | KF/KZ/MA/CRO/CTX/NOR/LEV | S83 L | D87N | S80I | + | − | − |
GBSF1611290 | KF/KZ/MA/CTX/CFP/NOR/ENR | S83 L | D87N | S80I | + | − | − |
GBSF1501026 | KF/KZ/MA/CTX/CFP/NOR/ENR | S83 L | D87N | S80I | + | + | − |
GBSF1512425 | KF/KZ/MA/CRO/CTX/NOR/ENR/LEV | S83 L | D87N | S80I | + | + | − |
GBSF1602098 | KF/KZ/MA/CRO/CTX/CFP/NOR/ENR/CIP | S83 L | D87Y | S80I | + | − | + |
GBSF1512433 | KF/KZ/MA/FOX/CRO/CTX/CFP/NOR/ENR/LEV | S83 L | D87N | S80I | + | + | − |