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Table 5 Univariate analysis of the 28-day mortality rate of K. pneumoniae BSI patients in the ICU

From: Clinical and molecular characteristics, risk factors and outcomes of Carbapenem-resistant Klebsiella pneumoniae bloodstream infections in the intensive care unit

Variable

Died (n = 21)

Survived (n = 27)

Univariate analysis

P

OR

95% CI

Sex (male, n)

Age (y) (mean ± SD)

57.74 ± 16.63

61.57 ± 13.69

0.448

  

APACHE II score at admission

11.50 ± 5.53

10.07 ± 4.95

0.406

  

APACHE II score on the day of bacteremia

18.29 ± 7.36

14.48 ± 6.11

0.031

  

Liver failurea at admission

7

8

0.784

1.188

0.348—4.051

Kidney failureb at Admission

4

7

0.574

0.672

0.168—2.694

Liver failure on the day of bacteremia

11

7

0.06

3.143

0.933—10.584

Kidney failure on the day of bacteremia

6

6

0.614

1.400

0.377—5.195

Co-infection

14

20

0.575

0.700

0.2—2.445

CRKp

12(57.1%)

19(70.3%)

0.342

0.561

0.170—1.856

Diabetes mellitus

5(23.8%)

9(23.3%)

0.371

0.556

0.152—2.027

Hypertension

10(47.6%)

14(51.9%)

0.771

0.844

0.270—2.644

Coronary heart disease

2(9.5%)

2(7.4%)

0.792

1.316

0.170—10.208

Chronic renal failure

2(9.5%)

4(14.8%)

0.582

0.605

0.1—3.672

Solid organ tumor

4(19%)

7(25.9%)

0.574

0.672

0.168—2.694

Surgery in the past medical history

2(9.5%)

6(22.2%)

0.242

0.368

0.066—2.050

Prior healthcare-associated exposure

8(38.1%)

8(29.6%)

0.537

1.462

0.437—4.889

Glucocorticoid

8

12

0.658

0.769

0.240—2.460

Immunosuppressor

2(9.5%)

1(3.7%)

0.409

2.737

0.231—32.430

Central venous catheterization

17(81%)

23(85.2%)

0.696

0.739

0.161—3.383

Trachea cannula

9(42.9%)

5(18.5%)

0.066

3.3

0.899—12.108

Tracheotomy

6(27.3%)

11(40.7%)

0.325

0.545

0.162—1.833

Urinary catheter

13(61.9%)

17(16.9%)

0.940

0.956

0.295—3.102

Abdominal cavity drainage- tube

6(28.6%)

14(51.9%)

0.105

0.371

0.111—1.247

Stomach tube

18(85.7%)

23(85.2%)

0.959

1.043

0.305—0.593

Intrathoracic drain

0

4(14.8%)

0.121

0.523

0.394—0.693

External ventricular drainage tube care

1(4.7%)

0

0.438

0.426

0.305—0.593

  1. Abbreviations: OR odds ratio, CI confidence interval, CRKp carbapenem-resistant Klebsiella pneumoniae
  2. aLiver failure was defined as a serum bilirubin level of >3 mg/dl and/or prothrombin time (PT) of <50% on day 5 after surgery or thereafter; in patients with jaundice, it was defined as an increase in the serum bilirubin level or a PT < 50% on day 5 or thereafter [49]
  3. bKidney failure was defined as a creatinine level of ≥2 mg/dl or requirement for dialysis [33]
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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