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Table 2 Use of carbapenems and other antibiotic classes in hospital wards across France, 2009–2013

From: Higher third-generation cephalosporin prescription proportion is associated with lower probability of reducing carbapenem use: a nationwide retrospective study

Antibiotic use, DDDs per 1000 patient-days (RC)a ICU wards, N = 85 Medical wards, N = 227 Surgical wards, N = 181
All antibiotics 1487 (−0.52%) 615 (−0.89%) 607 (+ 5.68%)
Carbapenems 73.4 (+ 5.65%) 6.2 (+ 24.1%) 5.4 (+ 25.1%)
  - Imipenem 62.1 (−0.74%) 5.3 (+ 13.9%) 4.2 (+ 27.5%)
  - Meropenem 5.3 (+ 285%) 0.36 (+ 195%) 0.23 (+ 109%)
  - Ertapenem 4.87 (−20.4%) 0.52 (+ 45.3%) 0.86 (− 13.3%)
  - Doripenem 1.17 (−16.7%) 0.04 (+ 208%) 0.06 (+ 1125%)
Aminopenicillins ± β-lactamase inhibitors 417 (−2.86%) 318 (−1.65%) 268 (+ 0.94%)
Piperacillin/tazobactam 90.1 (+ 34.7%) 8.6 (+ 79%) 8 (+ 109%)
Third-generation cephalosporins 205.9 (+ 0.78%) 60.4 (+ 18.9%) 38.1 (+33.2%)
Fluoroquinolones 177.2 (−24.2%) 88.4 (− 21.3%) 75.1 (−13.1%)
Aminoglycosides 106.1 (+3.35%) 12.4 (−6.98%) 25.4 (+ 13.8%)
Glycopeptides 59.6 (−23.2%) 9.8 (−5.1%) 10.3 (+ 23.6%)
Imidazoles 61.9 (−3.93%) 20.2 (+ 20.6%) 39.6 (+ 9.96%)
  1. DDD defined daily dose; ICU intensive care unit; RC relative change (%) between 2009 and 2013
  2. aPooled means in DDDs per 1000 patient-days and relative changes in percent