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Table 2 Use of carbapenems and other antibiotic classes in hospital wards across France, 2009–2013

From: Higher third-generation cephalosporin prescription proportion is associated with lower probability of reducing carbapenem use: a nationwide retrospective study

Antibiotic use, DDDs per 1000 patient-days (RC)a

ICU wards, N = 85

Medical wards, N = 227

Surgical wards, N = 181

All antibiotics

1487 (−0.52%)

615 (−0.89%)

607 (+ 5.68%)

Carbapenems

73.4 (+ 5.65%)

6.2 (+ 24.1%)

5.4 (+ 25.1%)

  - Imipenem

62.1 (−0.74%)

5.3 (+ 13.9%)

4.2 (+ 27.5%)

  - Meropenem

5.3 (+ 285%)

0.36 (+ 195%)

0.23 (+ 109%)

  - Ertapenem

4.87 (−20.4%)

0.52 (+ 45.3%)

0.86 (− 13.3%)

  - Doripenem

1.17 (−16.7%)

0.04 (+ 208%)

0.06 (+ 1125%)

Aminopenicillins ± β-lactamase inhibitors

417 (−2.86%)

318 (−1.65%)

268 (+ 0.94%)

Piperacillin/tazobactam

90.1 (+ 34.7%)

8.6 (+ 79%)

8 (+ 109%)

Third-generation cephalosporins

205.9 (+ 0.78%)

60.4 (+ 18.9%)

38.1 (+33.2%)

Fluoroquinolones

177.2 (−24.2%)

88.4 (− 21.3%)

75.1 (−13.1%)

Aminoglycosides

106.1 (+3.35%)

12.4 (−6.98%)

25.4 (+ 13.8%)

Glycopeptides

59.6 (−23.2%)

9.8 (−5.1%)

10.3 (+ 23.6%)

Imidazoles

61.9 (−3.93%)

20.2 (+ 20.6%)

39.6 (+ 9.96%)

  1. DDD defined daily dose; ICU intensive care unit; RC relative change (%) between 2009 and 2013
  2. aPooled means in DDDs per 1000 patient-days and relative changes in percent