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Table 1 Characteristics of patients receiving antibiotic prophylaxis with ceftriaxone and ampicillin (n = 4149)

From: The efficacy of ampicillin compared with ceftriaxone on preventing cesarean surgical site infections: an observational prospective cohort study

Characteristic Ceftriaxone (n = 911) Ampicillin (n = 3238) p-value
  n % n %  
Age (yr)
  < 20 24 2.6 209 6.5  
 20–34 691 75.9 2391 73.8  
  ≥ 35 196 21.5 638 19.7  
 Mean ± SD 30.2 ±5.3 28.9 ±6.2 < 0.001
Ethnic minority 130 14.3 1788 55.2 < 0.001
Education level
 None 88 9.7 1513 46.7 < 0.001
 Primary 99 10.9 598 18.5  
 Intermediate 236 25.9 673 20.8  
 College/higher 488 53.5 454 14.0  
Antenatal care
 No 3 0.3 72 2.2 < 0.001
 Camp 40 4.4 827 25.5  
 Hospital 868 95.3 2339 72.3  
Body weight (kg)
  ≥ 80 155 17.0 408 12.6  
 Mean ± SD 69.0 ±11.7 65.4 ±12.4 < 0.001
Hb (g/dL)
  < 11 145 15.9 617 19.1  
 Mean ± SD 11.5 ±1.0 11.4 ±1.2 0.008
HIV positive 5 0.6 124 3.8 < 0.001
Referral 48 5.3 1070 33.1 < 0.001
Gravida      
Primigravida 308 33.8 1140 35.2  
Median (IQR) 2 (1–2) 2 (1–3) 0.002
Multiple gestations 13 1.4 123 3.8 < 0.001
GA (weeks)
  < 37 26 2.9 425 13.1  
 Mean ± SD 38.6 ±1.3 38.4 ±2.4 0.152
PV ≥5 occasions before surgery 17 1.9 405 12.5 < 0.001
Amniotic fluid
 Clear 896 98.4 2757 85.2 < 0.001
 MSAF 11 1.2 468 14.4  
 Foul smelling 4 0.4 13 0.4  
ROM duration (hr)
 Median (IQR) 0 (0–0) 0 (0–2.3) < 0.001
Fetal death 5 0.6 38 1.2 0.136
ASA score ≥ 3 19 2.1 198 6.1 < 0.001
Wound class ≥3 15 1.7 364 11.2 < 0.001
Operation time (min)
  ≥ 55 93 10.2 1209 37.3  
 Median (IQR) 40 (35–45) 50 (40–60) < 0.001
Emergency 214 23.5 2487 76.8 < 0.001
EBL (mL)
  ≥ 500 121 13.3 1956 60.4  
 Median (IQR) 300 (300–400) 500 (400–500) < 0.001
UTI 1 0.1 9 0.3 0.701
Skin incision line      
 Midline 119 13.1 1492 46.1 < 0.001
 Pfannelstein 792 86.9 1746 53.9  
Addition procedures
 Appendectomy/TR 542 59.5 1432 44.2 < 0.001
Propensity score
 Mean ± SD 0.86 ±0.27 0.04 ±0.11 < 0.001
 Median (IQR) 0.96 (0.92–0.96) 0.02 (0.01–0.03) < 0.001
  1. ASA American Society of Anesthesiology, MSAF Meconium stained amniotic fluid, dL Decilitre, EBL Estimated blood loss, g Gram, GA Gestational age, Hb Hemoglobin, HIV Human immunodeficiency virus, hr. Hours, IQR Interquartile range, kg Kilogram, min Minute, PV Pelvic examinations, ROM Rupture of amniotic membranes, SD Standard deviation, SSIs Surgical site infections, TR Tubal resection, UTI Urinary tract infection, mL Millilitre, yr. Years