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Table 1 Baseline characteristics of patients enrolled in the study

From: Efficacy of intravenous plus intrathecal/intracerebral ventricle injection of polymyxin B for post-neurosurgical intracranial infections due to MDR/XDR Acinectobacter baumannii: a retrospective cohort study

Characteristic

ITV group (n = 38)

ITV + ITC group (n = 23)

P

Sex (male) (n, %)

20, 52.63%

10, 43.48%

0.488

Age (years)

53.50 ± 15.17

55.00 ± 15.08

0.761

Primary disease (n, %)

  

0.091

 Cerebral hemorrhage

30, 78.95%

14, 60.87%

 

 Craniocerebral trauma

4, 10.53%

2, 8.70%

 

 Benign Intracranial tumor

4, 10.53%

7, 30.43%

 

Comorbidities (n, %)

  

0.833

 Diabetes

3, 7.89%

4, 17.39%

 

 Cardiovascular disease

11, 28.95%

9, 39.13%

 

 Pulmonary disease

0, 0.00%

1, 4.35%

 

 Nervous system disease

1, 2.63%

1, 4.35%

 

Surgeries (n, %)

  

0.396

 Craniotomy evacuation of hematoma + decompressivecraniectomy

32, 84.21%

21, 91.27%

 

 Intracranial tumor resection

3, 7.89%

2, 8.70%

 

 Craniotomy aneurysm clipping

12, 31.58%

9, 39.13%

 

 Drainage of intracranial hematoma

9, 23.68%

7, 30.43%

 

 Ventricle peritoneal shunt

6, 15.79%

5, 21.74%

 

 Lumbar cistern drainage

26, 68.42%

15, 65.22%

 

 Ommaya reservoir

2, 5.26%

2, 8.70%

 

Coinfection (n, %)

  

0.727

 Lung

29, 76.32%

18, 78.26%

 

 Bloodstream

5, 13.16%

4, 17.39%

 

SOFA score

5.34 ± 3.02

5.08 ± 2.23

0.707

APACHE II score

18.55 ± 5.62

17.65 ± 4.90

0.513

Clinical symptoms

 Fever (°C)

39.02 ± 0.53

39.17 ± 0.48

0.256

  1. SOFA sequential organ failure assessment, APACHE acute physiology and chronic health evaluation. ITV intravenous, ITV + ITC intrathecal/intracerebral