TY - JOUR AU - Bougnoux, Marie-Elisabeth AU - Brun, Sophie AU - Zahar, Jean-Ralph PY - 2018 DA - 2018/03/27 TI - Healthcare-associated fungal outbreaks: New and uncommon species, New molecular tools for investigation and prevention JO - Antimicrobial Resistance & Infection Control SP - 45 VL - 7 IS - 1 AB - Outbreaks of healthcare-associated fungal infections have repeatedly been described over recent years, often caused by new or uncommon species. Candida auris, a recently described multidrug-resistant yeast species, is certainly the most worrisome species having caused several severe healthcare outbreaks of invasive infections, on four continents. Also, large nosocomial outbreaks due to uncommon fungal species such as Exserohilum rostratum and Sarocladium kiliense, were both linked to contamination of medical products, however the source of another outbreak, caused by Saprochaete clavata, remains unresolved. Furthermore, these outbreaks identified new populations under threat in addition to those commonly at risk for invasive fungal infections, such as immunosuppressed and intensive care unit patients. All of these outbreaks have highlighted the usefulness of a high level of awareness, rapid diagnostic methods, and new molecular typing tools such as Whole Genome Sequencing (WGS), prompt investigation and aggressive interventions, including notification of public health agencies. SN - 2047-2994 UR - https://doi.org/10.1186/s13756-018-0338-9 DO - 10.1186/s13756-018-0338-9 ID - Bougnoux2018 ER -