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Table 1 Drug resistance patterns among 1326 tuberculosis patients in Hangzhou, China, 2015

From: Prevalence and patterns of drug resistance among pulmonary tuberculosis patients in Hangzhou, China

  Type of TB resistance New cases (N = 1020) Treated cases (N = 306)
n % n %
Resistance to any first-line drugs 184 18.0 112 36.6
Resistance to individual drugs in any tests
 Isoniazid 102 10.0 89 29.1
 Rifampin 57 5.6 78 25.5
 Ethambutol 15 1.5 23 7.5
 Streptomycin 119 11.7 58 19.0
 Ofloxacin 20 2.0 15 4.9
 Kanamycin 7 0.7 4 1.3
Resistance to single drug only
 Isoniazid 33 3.2 15 4.9
 Rifampin 15 1.5 8 2.6
 Ethambutol 2 0.2 0 0
 Streptomycin 57 5.6 10 3.3
 Ofloxacin 14 1.4 3 1.0
 Kanamycin 2 0.2 0 0
Resistance to two drugs
 Isoniazid+ethambutol 1 0.1 1 0.3
 Isoniazid+streptomycin 27 2.7 3 1.0
 Rifampin+ethambutol 1 0.1 0 0
 Rifampin+streptomycin 3 0.3 1 0.3
 Ethambutol+streptomycin 1 0.1 1 0.3
 Rifampin+ofloxacin 0 0 1 0.3
 Streptomycin+ofloxacin 2 0.2 1 0.3
 Isoniazid+ofloxacin 1 0.1 1 0.3
 Streptomycin+ kanamycin 1 0.1 0 0
 Isoniazid+rifampin 9 0.9 19 6.2
Resistance to three drugs
 Isoniazid+rifampin+ethambutol 0 0 6 2.0
 Isoniazid+rifampin+Streptomycin 16 1.6 24 7.8
 Ethambutol+streptomycin+ofloxacin 0 0 1 0.3
 Isoniazid+rifampin+ofloxacin 1 0.1 1 0.3
 Isoniazid+rifampin+kanamycin 1 0.1 0 0
 Isoniazid+ethambutol+ofloxacin 0 0 1 0.3
Resistance to four drugs
 Isoniazid+rifampin+ethambutol+streptomycin 8 0.8 10 3.3
 Isoniazid+rifampin+ethambutol+ofloxacin 0 0 2 0.7
 Isoniazid+rifampin+streptomycin+ofloxacin 1 0.1 1 0.3
 Isoniazid+rifampin+streptomycin+kanamycin 0 0 2 0.7
Resistance to five drugs
 Isoniazid+rifampin+ethambutol+streptomycin+ofloxacin 0 0 2 0.7
 Isoniazid+rifampin+ethambutol+streptomycin+kanamycin 1 0.1 0 0
Multi-drug resistance (MDR) 38 3.7 68 22.2
Extensive drug resistance (XDR)
 Isoniazid+rifampin+ofloxacin+kanamycin (or cycloserine)a 1 0.1 2 0.7
  1. aOf these 3XDR patients, two were resistant to kanamycin, and one to cycloserine