Table 3 Prevalence trend of drug resistance among tuberculosis patients in Hangzhou, China, from 2011 to 2015
From: Prevalence and patterns of drug resistance among pulmonary tuberculosis patients in Hangzhou, China
Type of TB resistance | Treatment history | 2011 (N = 1184) | 2015 (N = 1326) | χ2 | P |
|---|---|---|---|---|---|
Resistance to any first-line drugs | All | 371 (31.3) | 296 (22.3) | 26.0 | < 0.01 |
New cases | 211 (23.4) | 184 (18.0) | 8.3 | < 0.01 | |
Treated cases | 160 (57.0) | 112 (36.6) | 24.4 | < 0.01 | |
Isoniazid | All | 231 (19.5) | 191 (14.4) | 11.7 | < 0.01 |
New cases | 103 (11.4) | 102 (10.0) | 1.0 | 0.32 | |
Treated cases | 128 (45.6) | 89 (29.1) | 17.1 | < 0.01 | |
Rifampin | All | 201 (17.0) | 135 (10.2) | 24.9 | < 0.01 |
New cases | 82 (9.1) | 57 (5.6) | 8.7 | < 0.01 | |
Treated cases | 119 (42.4) | 78 (25.5) | 18.7 | < 0.01 | |
Ethambutol | All | 60 (5.1) | 38 (2.9) | 8.1 | < 0.01 |
New cases | 13 (1.4) | 15 (1.5) | 0.0 | 0.95 | |
Treated cases | 47 (16.7) | 23 (7.5) | 11.8 | < 0.01 | |
Streptomycin | All | 203 (17.2) | 177 (13.4) | 7.0 | < 0.01 |
New cases | 110 (12.2) | 119 (11.7) | 0.1 | 0.73 | |
Treated cases | 93 (33.1) | 58 (19.0) | 15.3 | < 0.01 | |
Multi-drug resistance (MDR) | All | 137 (11.6) | 106 (8.0) | 9.2 | < 0.01 |
New cases | 37 (4.1) | 38 (3.7) | 0.2 | 0.67 | |
Treated cases | 100 (35.6) | 68 (22.2) | 12.8 | < 0.01 |