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Table 1 Additional β-lactamase genes in carbapenemase-producing K. pneumoniae isolates. Counts are given in exact numbers and in percentages. Genes were extracted from NGS data using ResFinder software

From: Genome-based analysis of Carbapenemase-producing Klebsiella pneumoniae isolates from German hospital patients, 2008-2014

  KPC-2 KPC-3 OXA-48 NDM-1 Total
n = 34 n = 26 n = 42 n = 5 n = 107
Chromosomal β-lactamase genes
blaSHV-1 2 (6%) 16 (38%) 1 (20%) 19 (18%)
blaSHV-11 25 (74%) 25 (96%) 21 (50%) 2 (40%) 73 (68%)
blaSHV-12 6 (18%) 6 (6%)
blaSHV-28 3 (7%) 2 (40%) 5 (5%)
blaSHV-77 1 (2%) 1 (1%)
blaLEN-16 1 (2%) 1 (1%)
blaLEN-27 1 (3%) 1 (1%)
Acquired β-lactamase genes
blaTEM-1 25 (74%) 23 (88%) 34 (81%) 3 (60%) 85 (80%)
blaOXA-1 1 (4%) 27 (64%) 2 (40%) 30 (28%)
blaOXA-9 1 (3%) 10 (24%) 1 (20%) 12 (11%)
blaCTX-M-14 4 (10%) 4 (4%)
blaCTX-M-15 1 (3%) 1 (4%) 15 (36%) 5 (100%) 22 (21%)
blaCMY-2 1 (2%) 1 (1%)
blaVEB-1 1 (3%) 1 (1%)