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Table 4 Agreement between phenotypically tested and whole genome sequence predicted antimicrobial resistance

From: Whole genome sequencing reveals high clonal diversity of Escherichia coli isolated from patients in a tertiary care hospital in Moshi, Tanzania

Antibiotic name

DSTa

WGSb

Agreement

Kappa

P value

Amoxicillin-Clavulanate

15 (62.5%)

14 (58.3%)

0.875

0.74

0.0001

Ampicillin

16 (66.7%)

14 (58.3%)

0.9167

0.82

0.00

Ceftazidime

13 (54.2%)

13 (54.2%)

0.9167

0.83

0.00

Ceftriaxone

15 (62.5)

13 (54.2%)

0.9167

0.84

0.00

Chloramphenicol

2 (8.3%)

2 (8.3%)

0.8333

−0.09

0.672

Ciprofloxacin

15 (62.5%)

14 (58.3%)

0.875

0.74

0.0001

Gentamycin

7 (29.2%)

7 (29.2%)

0.9167

0.79

0.00

Trimethoprim Sulpha

17 (70.8%)

4 (16.7%)

0.4583

0.15

0.0799

  1. a phenotype-based resistance
  2. b whole genome sequence-based resistance