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Table 5 Co-resistance of carbapenem non-susceptible K. pneumoniae isolates (n = 966) against other antibiotics

From: Carbapenem non-susceptibility of Klebsiella pneumoniae isolates in hospitals from 2011 to 2016, data from the German Antimicrobial Resistance Surveillance (ARS)

 

Isolates from all laboratories

Isolates from laboratories that routinely test against the specified antibiotica

Tested against

Included isolates

Non-susceptible isolates, % (95%CI)b

Included isolates

Non-susceptible isolates, % (95%CI)b

Ampicillin/ Sulbactam

871

93.0% (90.3, 95.0%)

c

c

Piperacillin/ Tazobactam

950

90.7% (87.4, 93.2%)

c

c

Ceftazidime

954

88.7% (85.8, 91.0%)

c

c

Cefotaxime

908

88.3% (85.0, 91.0%)

c

c

Polymyxin/ Colistin

435

13.3% (9.8, 17.9%)

214

14.0% (8.8, 21.7%)

Tigecycline

865

56.6% (51.0, 62.1%)

709

55.6% (49.1, 61.8%)

Fosfomycin

632

47.0% (40.6, 53.5%)

319

46.7% (36.2, 57.5%)

Gentamicin

960

57.8% (53.0, 62.4%)

c

c

Co-Trimoxazole

961

62.7% (57.6, 67.6%)

c

c

Ciprofloxacin

959

82.0% (78.4, 85.0%)

c

c

Nitrofurantoin

313

82.7% (76.3, 87.7%)

99

72.7% (60.0, 82.6%)

  1. R resistant, I intermediate, CI confidence interval
  2. aAnalysis restricted to laboratories that test > 90% of isolates against the specified antibiotic
  3. b95% CI calculated accounting for clustering by hospital
  4. cAntibiotic is routinely tested in all laboratories (> 90% of all isolates tested)