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Table 3 Cross-correlation coefficients between quarterly antibiotics prescriptions and quarterly isolation rates of antibiotic-resistant K pneumoniae from 2012 to 2016

From: Temporal association between antibiotic use and resistance in Klebsiella pneumoniae at a tertiary care hospital

Antibiotics Antibiotic-resistant Klebsiella pneumoniae
Piperacillin/tazobactam Ceftazidime Levofloxacin
β-lactam/β-lactamase inhibitors 0.66
p < 0.01
2 quarters lag
0.54
p = 0.02
2 quarters lag
−0.60
p = 0.01
2 quarters lag
Third-generation cephalosporins −0.11
p = 0.65
-
0.64
p < 0.01
2 quarters lag
0.50
p = 0.03
1 quarter lag
Fluoroquinolones 0.26
p = 0.29
-
0.14
p < 0.01
2 quarters lag
0.23
p = 0.35
-