| |
Resistance
|
Association with antibiotic use
|
|---|
|
No. of tests/strata
|
Proportion resistant (95% CI)
|
Odds ratio (95% CI)
|
p-value
|
|---|
|
Amoxicillin/Ampicillin
|
2330 / 139
|
62 (55–69)
|
1.08 (0.84–1.40)
|
0.53
|
|
Amoxicillin-clavulanic acid
|
2330 / 139
|
39 (35–44)
|
1.07 (1.02–1.12)
|
0.004
|
|
Ceftriaxone
|
1085 / 119
|
18 (13–24)
|
1.10 (0.68–1.76)
|
0.71
|
|
Cefepime
|
1083 / 119
|
8 (6–12)
|
1.06 (0.90–1.25)
|
0.49
|
|
Piperacillin-tazobactam
|
1085 / 119
|
17 (13–21)
|
2.11 (1.45–3.07)
|
< 0.001
|
|
Quinolones
|
2330 / 139
|
20 (17–23)
|
1.52 (1.25–1.86)
|
< 0.001
|
|
Trimethoprim-sulfamethoxazole
|
2329 / 139
|
32 (27–37)
|
1.59 (1.19–2.13)
|
0.002
|
|
Gentamicin
|
1085 / 119
|
18 (14–22)
|
1.30 (0.45–3.71)
|
0.63
|
|
Combined
|
13,657 / 1032
|
24 (15–36)
|
1.09 (1.04–1.14)
|
< 0.001
|
- Results from logistic mixed models for antibiotic resistance in relation to consumption. Odds ratios represent the change in the odds for resistance per increase in antibiotic use by 5 DDD/100 bed-days. Strata refer to year/department combinations
- CI confidence interval
