Skip to main content

Table 3 Univariate and Multivariate Cox Regression Analysis for the Risk for Subsequent Multidrug-resistant Gram-negative Bacteria (MDRGNB) Infection after Hospital Discharge

From: Risk for subsequent infection and mortality after hospitalization among patients with multidrug-resistant gram-negative bacteria colonization or infection

  Univariate analysis Multivariate analysis
HR (95% CI) p-value HR (95% CI) p-value
Age (per year increase) 1.03 (1.02–1.05) < 0.001 1.02 (1.01–1.03) 0.007
Male sex 0.97 (0.68–1.37) 0.84
LTCF residence 2.59 (1.43–4.70) 0.002
Long-term hemodialysis 1.30 (0.53–3.19) 0.56
Diabetes mellitus 1.13 (0.77–1.64) 0.53
Malignancy 1.41 (0.95–2.09) 0.09 1.66 (1.12–2.47) 0.012
End-stage renal disease 0.96 (0.39–2.34) 0.93
Liver cirrhosis 0.65 (0.32–1.33) 0.24
Congestive heart failure 2.79 (1.83–4.27) < 0.001 1.70 (1.08–2.68) 0.021
COPD 2.73 (1.80–4.15) < 0.001 1.60 (1.03–2.48) 0.038
Cerebrovascular accident 1.75 (1.17–2.64) 0.007
Presence of pressure sore 2.32 (1.31–4.12) 0.004
Central vascular cathetera,b 1.83 (1.01–3.32) 0.046
Long-term urinary catheterb 1.72 (1.00–3.00) 0.05
Antibiotics exposurec 3.54 (2.03–6.17) < 0.001 2.20 (1.25–3.90) 0.007
Intensive care unit admissionc 1.26 (0.59–2.70) 0.55
Receiving tracheal intubationc 2.39 (1.25–4.56) 0.008
MDRGNB culture positivec,d 7.19 (5.08–10.19) < 0.001 5.35 (3.72–7.71) < 0.001
  1. Abbreviations: LTCF long-term care facility, COPD chronic obstructive pulmonary disease
  2. aIncludes Port-A catheter, Hickman catheter, permcath catheter, double-lumen catheter, and peripherally inserted central catheter
  3. bAt the time of index hospitalization discharge
  4. cDuring index hospitalization
  5. dIncluding positive MDR-GNB culture from either surveillance or clinical culture of any anatomical site