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Table 3 Univariate and Multivariate Cox Regression Analysis for the Risk for Subsequent Multidrug-resistant Gram-negative Bacteria (MDRGNB) Infection after Hospital Discharge

From: Risk for subsequent infection and mortality after hospitalization among patients with multidrug-resistant gram-negative bacteria colonization or infection

 

Univariate analysis

Multivariate analysis

HR

(95% CI)

p-value

HR

(95% CI)

p-value

Age (per year increase)

1.03

(1.02–1.05)

< 0.001

1.02

(1.01–1.03)

0.007

Male sex

0.97

(0.68–1.37)

0.84

LTCF residence

2.59

(1.43–4.70)

0.002

Long-term hemodialysis

1.30

(0.53–3.19)

0.56

Diabetes mellitus

1.13

(0.77–1.64)

0.53

Malignancy

1.41

(0.95–2.09)

0.09

1.66

(1.12–2.47)

0.012

End-stage renal disease

0.96

(0.39–2.34)

0.93

Liver cirrhosis

0.65

(0.32–1.33)

0.24

Congestive heart failure

2.79

(1.83–4.27)

< 0.001

1.70

(1.08–2.68)

0.021

COPD

2.73

(1.80–4.15)

< 0.001

1.60

(1.03–2.48)

0.038

Cerebrovascular accident

1.75

(1.17–2.64)

0.007

Presence of pressure sore

2.32

(1.31–4.12)

0.004

Central vascular cathetera,b

1.83

(1.01–3.32)

0.046

Long-term urinary catheterb

1.72

(1.00–3.00)

0.05

Antibiotics exposurec

3.54

(2.03–6.17)

< 0.001

2.20

(1.25–3.90)

0.007

Intensive care unit admissionc

1.26

(0.59–2.70)

0.55

Receiving tracheal intubationc

2.39

(1.25–4.56)

0.008

MDRGNB culture positivec,d

7.19

(5.08–10.19)

< 0.001

5.35

(3.72–7.71)

< 0.001

  1. Abbreviations: LTCF long-term care facility, COPD chronic obstructive pulmonary disease
  2. aIncludes Port-A catheter, Hickman catheter, permcath catheter, double-lumen catheter, and peripherally inserted central catheter
  3. bAt the time of index hospitalization discharge
  4. cDuring index hospitalization
  5. dIncluding positive MDR-GNB culture from either surveillance or clinical culture of any anatomical site