Table 6 Baseline characteristics prior to hospitalization for 35 patients (with MRSA) and 452 controls (without MRSA)
Baseline characteristics | MRSA (n = 35) | No MRSA (n = 452) | p-value |
|---|---|---|---|
Mean age ± SD (years) | 66.7 ± 20.1 | 61.3 ± 17.6 | 0.09 |
Male gender | 22 (62.9%) | 244 (54.0%) | 0.31 |
Previous hospitalization | 23 (65.7%) | 188 (41.6%) | 0.006 |
Transfer status | |||
From other hospital | 5 (14.3%) | 52 (11.3%) | 0.59 |
From a long-term care facility | 0 | 6 (1.3%) | 1.00 |
Underlying diseases | |||
Any underlying disease | 31 (88.6%) | 389 (86.1%) | 0.68 |
Hypertension | 22 (62.9%) | 268 (59.3%) | 0.68 |
Diabetes mellitus | 13 (37.1%) | 172 (38.1%) | 0.92 |
Cardiovascular disease | 12 (34.3%) | 121 (26.8%) | 0.34 |
Cerebrovascular disease | 15 (42.9%) | 82 (18.1%) | < 0.001 |
Chronic liver disease | 5 (14.3%) | 83 (18.4%) | 0.55 |
Chronic renal disease | 3 (8.6%) | 61 (13.4%) | 0.60 |
Chronic lung disease | 5 (14.3%) | 58 (12.8%) | 0.79 |
Malignancy | 6 (17.1%) | 81 (17.9%) | 0.91 |
Solid malignancy | 5 (14.3%) | 70 (15.5%) | 0.85 |
Hematologic malignancy | 1 (2.9%) | 11 (2.4%) | 0.60 |
Hematologic diseases | 3 (8.6%) | 44 (9.7%) | 1.00 |
Prior organ transplantation | 0 | 7 (1.6%) | 1.00 |
Receipt of any immunosuppressive agent | 4 (11.4%) | 55 (12.2%) | 1.00 |
HIV infection | 1 (2.9%) | 15 (3.3%) | 1.00 |
Previous antibiotic exposure within 90 days after hospitalization | |||
Any antibiotic | 19 (54.3%) | 129 (28.5%) | 0.001 |
Penicillins | 2 (5.7%) | 17 (3.8%) | 0.64 |
Cephalosporins | 6 (17.1%) | 54 (12.0%) | 0.37 |
Carbapenems | 6 (17.1%) | 27 (6.0%) | 0.01 |
Beta-lactam/beta-lactamase inhibitor | 5 (14.3%) | 22 (4.9%) | 0.02 |
Fluoroquinolones | 9 (25.7%) | 37 (8.2%) | 0.001 |
Macrolides | 2 (5.7%) | 17 (3.8%) | 0.64 |
Others | 5 (14.3%) | 37 (8.2%) | 0.22 |
Previous use of indwelling catheters | |||
Urinary catheter | 13 (37.1%) | 32 (7.1%) | < 0.001 |
Nasogastric tube | 13 (37.1%) | 60 (13.3%) | < 0.001 |