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Table 3 Univariate analysis on risk factors for in-hospital death

From: The importance of adjusting for enterococcus species when assessing the burden of vancomycin resistance: a cohort study including over 1000 cases of enterococcal bloodstream infections

Parameter Discharge alive (n = 781) In-hospital death (n = 379) *P-value OR (CI 95)
Vancomycin resistance 6.7% (52) 13.7% (52) < 0.001 2.273 (1.512-3.417)
E. faecium 44.7% (349) 65.2% (247) < 0.001 2.311 (1.792-2.979)
E. faecalis 55.3% (432) 34.8% (132) 1 = Reference
Male 61.2% (478) 62.0% (235) 0.792 1.037 (0.805-1.334)
Age (years), median (IQR) 64.0 (51–73) 66.0 (56–74) 0.011 n.a.
Heart disease 25.1% (196) 35.4% (134) < 0.001 1.641 (1.258-2.14)
Vascular disease 19.6% (153) 27.7% (105) 0.002 1,57 (1,18-2.091)
Lung disease 19.6% (153) 26.1% (99) 0.011 1.461 (1.093-1.952)
Rheumatic disease 2.6% (20) 4.7% (18) 0.050 1.895 (0,99-3.626)
Gastrointestinal disease 4.1% (32) 5.8% (22) 0.195 1,44 (0,825-2.515)
Diabetes 26.8% (209) 27.4% (104) 0.807 1.033 (0,784-1.361)
Renal disease 46.9% (366) 78.1% (296) < 0.001 4.055 (3.061-5.371)
Liver disease 18.2% (142) 42.2% (160) < 0.001 3.283 (2.498-4.314)
Cancer/Immunological disease 41.4% (323) 45.4% (172) 0.194 1.176 (0,918-1.506)
Neurological disease 10.8% (84) 9.0% (34) 0.346 0,817 (0.537-1.241)
  1. Categorical variables displayed as percentage and number; continuous variable displayed as median and interquartile range. *P-value, categorical variables tested with Chi-square test, continuous variable tested with Wilcoxon rank sum test. BSI = blood stream infection, IQR = interquartile range, OR = odds ratio, CI95 = 95% confidence interval. VRE = vancomycin-resistant enterococcus, VSE = vancomycin-susceptible enterococcus. N.a. = not applicable
  2. Bold entries represent statistically significant factors