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Table 3 Univariate analysis on risk factors for in-hospital death

From: The importance of adjusting for enterococcus species when assessing the burden of vancomycin resistance: a cohort study including over 1000 cases of enterococcal bloodstream infections

Parameter

Discharge alive (n = 781)

In-hospital death (n = 379)

*P-value

OR (CI 95)

Vancomycin resistance

6.7% (52)

13.7% (52)

< 0.001

2.273 (1.512-3.417)

E. faecium

44.7% (349)

65.2% (247)

< 0.001

2.311 (1.792-2.979)

E. faecalis

55.3% (432)

34.8% (132)

1 = Reference

Male

61.2% (478)

62.0% (235)

0.792

1.037 (0.805-1.334)

Age (years), median (IQR)

64.0 (51–73)

66.0 (56–74)

0.011

n.a.

Heart disease

25.1% (196)

35.4% (134)

< 0.001

1.641 (1.258-2.14)

Vascular disease

19.6% (153)

27.7% (105)

0.002

1,57 (1,18-2.091)

Lung disease

19.6% (153)

26.1% (99)

0.011

1.461 (1.093-1.952)

Rheumatic disease

2.6% (20)

4.7% (18)

0.050

1.895 (0,99-3.626)

Gastrointestinal disease

4.1% (32)

5.8% (22)

0.195

1,44 (0,825-2.515)

Diabetes

26.8% (209)

27.4% (104)

0.807

1.033 (0,784-1.361)

Renal disease

46.9% (366)

78.1% (296)

< 0.001

4.055 (3.061-5.371)

Liver disease

18.2% (142)

42.2% (160)

< 0.001

3.283 (2.498-4.314)

Cancer/Immunological disease

41.4% (323)

45.4% (172)

0.194

1.176 (0,918-1.506)

Neurological disease

10.8% (84)

9.0% (34)

0.346

0,817 (0.537-1.241)

  1. Categorical variables displayed as percentage and number; continuous variable displayed as median and interquartile range. *P-value, categorical variables tested with Chi-square test, continuous variable tested with Wilcoxon rank sum test. BSI = blood stream infection, IQR = interquartile range, OR = odds ratio, CI95 = 95% confidence interval. VRE = vancomycin-resistant enterococcus, VSE = vancomycin-susceptible enterococcus. N.a. = not applicable
  2. Bold entries represent statistically significant factors