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Table 2 Changes in outcomes after the intervention of SAP

From: Optimal timing of surgical antimicrobial prophylaxis in laparoscopic surgery: a before-after study

 

Pre-intervention

(n = 942)

Intervention

(n = 455)

P value

SAP, n (%)

940 (99.8)

455 (100)

 

SAP drip infusion time, median, (IQR) min

16 (13–20)

23 (17–30)

<  0.001

Time from SAP completion to surgical incision, median, (IQR) min

8 (2–16)

26 (15–35)

<  0.001

Time windows, n (%)

  > 120 min

13 (1.4)

3 (0.7)

0.18

 61–120 min

11 (1.2)

5 (1.1)

0.57

 31–60 min

56 (5.9)

161 (35.4)

<  0.001

 0–30 min

702 (74.5)

278 (61.1)

<  0.001

 <  0 min

158 (16.8)

8 (1.8)

<  0.001

SSI, n (%)

130 (13.8)

60 (13.2)

0.80

Type of SSI, n (%)

 Superficial SSI

78 (8.3)

35 (7.7)

0.71

 Deep SSI

0 (0)

4 (0.9)

N/A

 Organ-space SSI

52 (5.5)

21 (4.6)

0.48

  1. Abbreviations: SAP surgical antimicrobial prophylaxis, IQR interquartile range, SSI surgical site infection, N/A not applicable