Table 2 Clinical outcomes of patients with community-acquired (CA), healthcare-associated (HCA), and nosocomial K. pneumoniae bacteremia
Variable | CA (n = 70) | HCA (n = 102) | Nosocomial (n = 165) | p value | ||
|---|---|---|---|---|---|---|
CA vs. HCA | HCA vs. Nosocomial | CA vs. Nosocomial | ||||
Appropriate empirical antimicrobial therapy | 68 (97.1) | 91 (89.2) | 133 (80.6) | 0.077 | 0.063 | < 0.001 |
Appropriate definite antimicrobial therapy | 65 (92.9) | 93 (91.2) | 138 (83.6) | 0.692 | 0.080 | 0.059 |
Length of stay after bacteremia, median (IQR), days | 14.0 (8.0–23.8) | 16.0 (9.8–28.0) | 17.0 (7.0–30.5) | 0.191 | 0.685 | 0.406 |
Septic shock when bacteremia | 15 (21.4) | 35 (34.3) | 58 (35.2) | 0.068 | 0.889 | 0.038 |
Respiratory failure requiring mechanical ventilation | 6 (8.6) | 14 (13.7) | 9 (5.5) | 0.300 | 0.019 | 0.371 |
Mortality | ||||||
In-hospital mortality | 12 (17.1) | 25 (24.5) | 67 (40.6) | 0.248 | 0.007 | < 0.001 |
Crude 28-day mortality | 10 (14.3) | 18 (17.6) | 51 (30.9) | 0.557 | 0.016 | 0.008 |