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Table 1 Interventions undertaken to curtail the epidemic spread of CRKP in 4 cumulative stages a

From: Infection-prevention and control interventions to reduce colonisation and infection of intensive care unit-acquired carbapenem-resistant Klebsiella pneumoniae: a 4-year quasi-experimental before-and-after study

Intervention

Description

Date begun

Baseline period

No intervention and regular surveillance cultures

Jan 2013- June 2013

Period 1

1. Active surveillance cultures

2. De-escalation interventions

July 2013–June 2014

2.1 First level interventions

 • contact precautions

 • patient isolation: single room isolation or cohorting

 • cohorting of medical care

 • disinfection and sterilization

2.2 Second level interventions

 • contact precautions

 • disinfection and sterilization

IPC interventions

2.3 Third level interventions

 • disinfection and sterilization

3. Target bundles interventions

 • intravascular catheter-related infection

 • ventilation associated pneumonia

 • catheter-associated urinary tract infection

 • skin and soft tissue infections.

Period 2

1. Active surveillance cultures

2. Modified de-escalation interventions

July 2014–June 2015

Modified

IPC interventions

+ Enhanced external medical staff education

+ Contact precautions of shared equipment

+ Enhanced terminal room disinfection

 

2.1 First level interventions (as Period 1)

2.2 Second level interventions (as Period 1)

2.3 Third level interventions (as Period 1)

3. Target bundles interventions (as Period 1)

Period 3

Follow up period 2

July 2015–June 2016

  1. aThe procedures of infection control interventions are explicated in detail in the section of Materials and Methods
  2. IPC Infection prevention and control, CRKP Carbapenem-resistant Klebsiella pneumoniae