Infection-prevention and control interventions to reduce colonisation and infection of intensive care unit-acquired carbapenem-resistant Klebsiella pneumoniae: a 4-year quasi-experimental before-and-after study

Table 4 Monthly incidence rates of totally CRKP colonization/ infection and ICU-acquired CRKP (No. of cases per 1000 ICU patient-days)

Intervention (period)	Incidence				Incidence
	No. of cases per 1000 ICU patient-days (totally CRKP)				No. of cases per 1000 ICU patient-days (ICU-acquired CRKP)
	Mean	Median	P^a	P^b	Mean	Median	P^c	P^d
Baseline period	10.33 ± 7.05	10.08 (4.43–17.46)	/	/	9.88 ± 6.44	10.08 (4.43–16.43)	/	/
Period 1	5.05 ± 4.25	3.18 (2.98–6.18)	0.014	/	4.30 ± 3.2	3.12 (2.98–5.40)	0.024	/
Period 2	4.94 ± 3.18	5.76 (2.77–6.34	0.013	0.945	4.47 ± 3.46	5.62 (0.69–6.34)	0.032	0.9
Period 3	5.88 ± 2.81	5.78 (3.52–8.47)	0.037	0.577	3.05 ± 1.42	2.84 (2.80–2.89)	0.021	0.032

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