Table 7 Benefits and Costs of a Comprehensive CDI Prevention Program 2015–2020 (2015 $) Using Age Adjusted VSL Estimates
| Â | 7% discount rate, 10% effectiveness | 3% discount rate, 10% effectiveness | 7% discount rate, 50% effectiveness | 3% discount rate, 50% effectiveness |
|---|---|---|---|---|
Total Intervention Costs (in billions) | $3.7 | $4.7 | $3.3 | $4.2 |
Total Benefits (in billions) | ||||
Direct Medical Cost Savings | ||||
  Savings in Patient Care Costs | $1.5 | $1.8 | $7.6 | $9.1 |
  Savings in Expenditures for Antibiotics | $3.8 | $4.2 | $3.8 | $4.2 |
Benefits of Morbidity Risk Reduction | ||||
  Low $/Lost QALY from HCA-CDI | $0.5 | $0.4 | $2.6 | $2.0 |
  Central $/ Lost QALY from HCA-CDI | $1.0 | $0.9 | $5.1 | $4.3 |
  High $/ Lost QALY from HCA-CDI | $1.6 | $1.3 | $7.8 | $6.5 |
Benefits of Mortality Risk Reduction | ||||
 Low VSL | ||||
  35% Attributable Mortality Proportion | $2.4 | $2.0 | $12.2 | $10.1 |
  50% Attributable Mortality Proportion | $3.5 | $2.9 | $17.3 | $14.5 |
 Central VSL | ||||
  35% Attributable Mortality Proportion | $5.1 | $4.3 | $25.5 | $21.4 |
  50% Attributable Mortality Proportion | $7.3 | $6.1 | $35.0 | $30.6 |
 High VSL | ||||
  35% Attributable Mortality Proportion | $7.8 | $6.5 | $39.0 | $32.7 |
  50% Attributable Mortality Proportion | $11.3 | $9.3 | $55.7 | $46.7 |
Range of Total Net Benefits | ||||
  Low | $4.5 - $5.6 | $3.7 - $4.6 | $22.9 - $28.0 | $21.2 - $25.6 |
  Central | $7.7 - $9.9 | $6.5 - $8.3 | $38.7 - $48.2 | $34.8 - $44.0 |
  High | $11.0 - $14.5 | $9.1 - $11.9 | $54.9 - $71.6 | $48.3 - $62.3 |