Effects of an antimicrobial stewardship intervention on perioperative antibiotic prophylaxis in pediatrics

Table 4 Choice of antibiotic for PAP and time of discontinuation of antibiotics after surgical procedure

Choice of antibiotic for PAP^a	Pre-intervention (n = 184)	Post-intervention (n = 153)	p-value
Monotherapy	n = 137	n = 124
Correct	111 (81%)	114 (91.9%)	0.02
Not correct	26 (19%)	10 (8.1%)	0.02
Combination therapy	n = 47	n = 29
Correct	31 (65.9%)	29 (100%)	0.004
Not correct	16 (34%)	0 (0%)	0.004
Discontinuation within 24 h	n = 184	n = 153
Yes	83 (45.1%)	102 (66.7%)	< 0.001
No	101 (54.9%)	51 (33.3%)	< 0.001

^achoice of monotherapy versus combination therapy was considered correct according to the guidelines’ recommendations

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