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Table 3 Literature synthesis of key outcomes: results and ranges

From: Value of hospital antimicrobial stewardship programs [ASPs]: a systematic review

 

# Studies Reporting Reductions or No Change

Range

# Studies Reporting Increases

Range

Patient Outcomes

 LOS

58

−21.9 to 0 days

10

0.1 to 5 days

 All-cause mortality rate

41

−18.1 to 0%

13

0.02 to 11%

 Infection-related mortality ratea

9

−12.0 to 0%

3

1 to 2.9%

 All-cause readmission rate

13

−12 to 0%

8

0.2 to 8.6%

  o 28/30-day

9

−10.86 to 0%

5

0.2 to 8.6%

 Infection-related readmission rate

8

−2.94% to − 0.8%

2

0.3 to 0.65%

  o 28/30-day

7

−2.94% to −0.7%

1

0.65%

Cost Outcomes

 Implementation costs

0

N/A

9

$2.5 k to $39.9 k

 Annual operational costsa

11

−72.4% to − 12.9%

5

7.9 to 243%

 Antibiotic costs

80

−80.1% to − 0.06%

7

4.1 to 51.5%

 LOS costsb

2

-$18.3 k to -$1.95 M

0

N/A

 Overall hospital costsb

32

-$9.11 k to -$2.06 M

0

N/A

  1. aIn these rows, the studies in the 2 columns are not mutually exclusive since more than 1 outcome was evaluated
  2. bOnly included studies measuring cost outcomes in USDN/A = Not Applicable